Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | GYS1 | P13807 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997613 | 0.62 | MEN1 (0.43) | AHRCA12CA9MEN1HTT | |
| SCHEMBL29769221 | 0.60 | AHR (1.00) | AHRMEN1HTTKMT2ACYP1B1 | |
| SCHEMBL137915 | 0.60 | AHR (1.00) | AHRMEN1HTTKMT2ACYP1B1 | |
| SCHEMBL4144378 | 0.59 | MEN1 (0.39) | AHRCA12CA9PGRMEN1 | |
| SCHEMBL8773713 | 0.58 | AHR (0.70) | AHRMEN1HTTKMT2ACYP1B1 | |
| SCHEMBL6335821 | 0.58 | AHR (0.70) | AHRMEN1KMT2ACYP1B1 | |
| SCHEMBL7906570 | 0.58 | AHR (0.70) | AHRMEN1HTTKMT2ACYP1B1 | |
| SCHEMBL10540728 | 0.58 | AHR (0.70) | AHRMEN1HTTKMT2ACYP1B1 | |
| SCHEMBL5843666 | 0.57 | CYP3A4 (0.71) | AHRCA12CA9MEN1HTT | |
| SCHEMBL11544490 | 0.56 | SCN9A (0.58) | AHRMEN1KMT2ACYP1B1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849744-B2 | α-phenyl-β-keto sulfones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | FISCHER REINER (DE) | 2004-04-01 | — | — | US | disclosed |
| US-6670385-B1 | Fungicides, herbicides and insecticides for crops | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
| EP-1185518-A1 | ALPHA-PHENYL-BETA-KETOSULFONE | Bayer Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000073289-A1 | ALPHA-PHENYL-BETA-KETOSULFONE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | CYP2S1, SULT1E1, SKP1 | AHR 496/4885CA12 4714/4885CA9 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.