SCHEMBL137915

SCHEMBL137915

Clc1ccc(-c2ccc(Cl)c(Cl)c2)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 1.00
CYP1B1 Q16678 1/20 0.78
TP53 P04637 1/20 0.56
TSHR P16473 3/20 0.52
CYP3A4 P08684 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 1/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
KMO O15229 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
HSD17B10 Q99714 1/20 0.50
NOTUM Q6P988 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
ALOX12 P18054 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29769221 1.00 AHR (1.00) AHRCYP1B1TP53TSHRCYP3A4
SCHEMBL1520954 0.88 AHR (0.78) AHRCYP1B1TP53TSHRCYP3A4
SCHEMBL30073229 0.88 AHR (0.78) AHRCYP1B1TP53TSHRCYP3A4
Polychlorinated Biphenyl 126 SCHEMBL6535350 0.88 AHR (1.00) AHRCYP1B1TP53TSHRCYP3A4
Polychlorinated Biphenyl 126 SCHEMBL308662 0.88 AHR (1.00) AHRCYP1B1TP53TSHRCYP3A4
Polychlorinated Biphenyl 126 SCHEMBL6942325 0.88 AHR (1.00) AHRCYP1B1TP53TSHRCYP3A4
SCHEMBL1443418 0.86 AHR (0.74) AHRCYP1B1TSHRALDH1A1KMO
SCHEMBL29493845 0.86 AHR (0.74) AHRCYP1B1TSHRALDH1A1KMO
SCHEMBL29776914 0.86 AHR (0.74) AHRCYP1B1TP53TSHRCYP3A4
SCHEMBL4454434 0.86 AHR (0.74) AHRCYP1B1TP53TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1007 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098519-A1 RADIOLIGAND COMPOUNDS AND USES THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2026-05-15 WO claimed
CN-118817890-A Method for measuring polychlorinated biphenyl of PCB194 and PCB206 in water body 河北省产品质量监督检验研究院 2024-10-22 CN claimed
EP-3126376-B1 POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS UNIV MONASH (AU) 2024-08-21 EP claimed
EP-4414356-A2 HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYL ESTER WITH REDUCED ENVIRONMENTAL POLLUTANTS, AND METHOD FOR PRODUCING SAME Nissui Corporation (JP) 2024-08-14 EP claimed
EP-3971165-B1 HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYL ESTER WITH REDUCED ENVIRONMENTAL POLLUTANTS, AND METHOD FOR PRODUCING SAME NISSUI CORP (JP) 2024-08-07 EP claimed
CN-117384794-B Amycolatopsis sp.MT3 and application thereof in degrading halogenated pollutants 中国科学院南京土壤研究所 2024-07-30 CN claimed
CN-117571845-A Method for rapidly and efficiently detecting organic chlorine and polychlorinated biphenyl in soil simultaneously 济南市环境研究院(济南市黄河流域生态保护促进中心) 2024-02-20 CN claimed
CN-117384794-A Amycolatopsis sp.MT3 and application thereof in degrading halogenated pollutants 中国科学院南京土壤研究所 2024-01-12 CN claimed
CN-116893235-A Method and kit for determining polychlorinated biphenyl and multi-class brominated flame retardant residues in traditional Chinese medicine 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) 2023-10-17 CN claimed
CN-111272723-B Method for detecting 3,3', 4' -tetrachlorobiphenyl in water environment by catalyzing hairpin self-assembly reaction based on biological aptamer 齐鲁工业大学 2023-08-22 CN claimed
US-20110097303-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING VIRAL INFECTIONS ENTERIN, INC. 2011-04-28 US claimed
US-20100267829-A1 Pharmaceutical composition comprising low concentrations of environment pollutants PRONOVA BIOPHARMA NORGE 2010-10-21 US claimed
US-20100233281-A1 PROCESS FOR DECREASING ENVIRONMENTAL POLLUTANTS IN AN OIL OR A FAT. PRONOVA BIOPHARMA NORGE AS 2010-09-16 US claimed
US-6544773-B1 For degrading different congeners namely coplanar, sterically hindered and other chlorobiphenyls COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2003-04-08 US claimed
US-20030054538-A1 Microbial process for degradation of PCBs in clophen A-50 using a novel marine microorganism, pseudomonas CH07 SARKAR ANUPAM (IN) 2003-03-20 US claimed
US-6204005-B1 ACCURATE AND SENSITIVE QUALITATIVE OR QUANTITATIVE ANALYSIS BY INCUBATING ANTIBODIES AND COMPETITOR OF DEFINED STRUCTURE IN PRESENCE OF TEST SAMPLE, THEN DETECTING CONGENER ECOCHEM RESEARCH, INC. 2001-03-20 US claimed
US-5877389-A Process for the oxidative decomposition of organic compounds present in aqueous effluents ELF AQUITAINE (FR) 1999-03-02 US claimed
US-5854010-A Bioassay for detecting 2,3,7,8-tetrachlorodibenzo-para-dioxin and TCDD-like compounds and novel recombinant cell line useful therefor XENOBIOTIC DETECTION SYSTEMS INTERNATIONAL, INC. 1998-12-29 US claimed
EP-0748296-B1 METHOD FOR OXIDATIVELY DECOMPOSING ORGANIC COMPOUNDS IN AQUEOUS EFFLUENTS ELF AQUITAINE (FR) 1997-08-27 EP claimed
US-5342779-A Using ultraviolet and fungicide resistant Phanerochaete chrysosporium THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-08-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110097303-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING VIRAL INFECTIONS STING1, IFNG, TSLP AHR 2810/4885CYP1B1 3347/4885TP53 3054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.