Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | CBFB | Q13951 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951979 | 0.86 | SOS1 (0.45) | HTR7HTR1DHTR2AHTR2CHTR1E | |
| SCHEMBL5952867 | 0.82 | SOS1 (0.47) | HTR7HTR1DHTR2AHTR2CHTR1E | |
| SCHEMBL5952436 | 0.76 | PDPK1 (0.43) | HTR7HTR1DHTR2AHTR2CHTR1E | |
| SCHEMBL18934294 | 0.74 | HTR7 (0.80) | HTR7HTR1DHTR2AHTR2CHTR1E | |
| SCHEMBL23567455 | 0.72 | ITK (0.59) | — | |
| SCHEMBL4947379 | 0.71 | AURKA (0.55) | SOS1 | |
| SCHEMBL5952112 | 0.70 | MAPT (0.46) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5952714 | 0.70 | MAPT (0.49) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5952998 | 0.69 | MAPT (0.44) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL16200134 | 0.67 | SOS1 (0.51) | HTR7HTR1DHTR2AHTR2CHTR1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897208-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-24 | — | — | US | claimed |