Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.66 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.66 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954288 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 | |
| SCHEMBL10352073 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 | |
| SCHEMBL10631075 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 | |
| SCHEMBL25216293 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 | |
| SCHEMBL11587025 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 | |
| SCHEMBL25211928 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 | |
| SCHEMBL19821301 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 | |
| SCHEMBL25266744 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 | |
| SCHEMBL11680438 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 | |
| SCHEMBL7565249 | 0.98 | KDM5A (0.69) | KDM5AKDM4CPHF8AKR1B1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878846-B2 | Solvent systems | RHODIA CONSUMER SPECIALTIES LTD. (GB) | 2005-04-12 | — | — | US | claimed |
| US-6452030-B1 | HYDROXYALKYL CONTAINING BETAINES FROM REACTING AN ALANINE DERIVATIVE AND A MONOOXIRANE; ESTERIFYING THE HYDROXYL GROUP WITH ANHYDRIDE OR MONO- OR DICARBOXYLIC ACID; BIODEGRADABLE; SURFACTANTS, BACTERICIDES, ANTISTATIC AGENTS, SOFTENERS | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-09-17 | — | — | US | disclosed |
| US-4927814-A | Diphosphonate derivatives, pharmaceutical compositions and methods of use | BOEHRINGER MANNHEIM GMBH (DE) | 1990-05-22 | — | — | US | disclosed |