SCHEMBL6284945

SCHEMBL6284945

CCNC(=O)NCC(C)S

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 5/20 0.41
MAPT P10636 2/20 0.37
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
PTGS2 P35354 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ACE P12821 2/20 0.33
MME P08473 1/20 0.33
CPA1 P15085 1/20 0.33
ACE2 Q9BYF1 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
EPHX2 P34913 1/20 0.33
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL965868 0.81 EPHX1 (0.59) EPHX1MAPTCYP2D6CYP2C19ALDH1A1
SCHEMBL6290263 0.79 EPHX1 (0.62) EPHX1ALDH1A1LMNATDP1SMN1; SMN2
SCHEMBL6289558 0.79
SCHEMBL6286430 0.79 EPHX1 (0.42) EPHX1MAPTCYP2D6CYP2C19ALDH1A1
SCHEMBL13681843 0.79 EPHX1 (0.42) EPHX1MAPTCYP2D6CYP2C19ALDH1A1
SCHEMBL23652165 0.77 EPHX1 (0.41) EPHX1MAPTCYP2D6CYP2C19ALDH1A1
SCHEMBL28293734 0.77 MMP1 (0.48) EPHX1ALDH1A1SMN1; SMN2MMP1MMP2
SCHEMBL320068 0.77
SCHEMBL6286865 0.76 EPHX1 (0.40) EPHX1MAPTCYP2D6CYP2C19ALDH1A1
SCHEMBL6290267 0.76 EPHX1 (0.40) EPHX1MAPTCYP2D6CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed