Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FUCA1 | P04066 | 5/20 | 0.44 |
| ▸ | ARG1 | P05089 | 1/20 | 0.44 |
| ▸ | FUCA2 | Q9BTY2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.41 |
| ▸ | MAN2B2 | Q9Y2E5 | 1/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971521 | 1.00 | PKM (0.45) | PKMFUCA1ARG1FUCA2ALDH1A1 | |
| SCHEMBL12909445 | 1.00 | PKM (0.45) | PKMFUCA1ARG1FUCA2ALDH1A1 | |
| SCHEMBL944158 | 1.00 | PKM (0.45) | PKMFUCA1ARG1FUCA2ALDH1A1 | |
| SCHEMBL942167 | 1.00 | PKM (0.45) | PKMFUCA1ARG1FUCA2ALDH1A1 | |
| SCHEMBL941276 | 1.00 | PKM (0.45) | PKMFUCA1ARG1FUCA2ALDH1A1 | |
| SCHEMBL15599050 | 1.00 | PKM (0.45) | PKMFUCA1ARG1FUCA2ALDH1A1 | |
| SCHEMBL24518229 | 1.00 | PKM (0.45) | PKMFUCA1ARG1FUCA2ALDH1A1 | |
| SCHEMBL17795749 | 1.00 | PKM (0.45) | PKMFUCA1ARG1FUCA2ALDH1A1 | |
| SCHEMBL12325135 | 1.00 | PKM (0.45) | PKMFUCA1ARG1FUCA2ALDH1A1 | |
| Water SCHEMBL17784184 | 0.98 | PKM (0.43) | PKMFUCA1ARG1FUCA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927294-B1 | Nitrogen-containing heterocycles | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-08-09 | — | — | US | disclosed |