Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | POLG | P54098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598983 | 0.82 | ABL1 (0.47) | DCKALDH1A1HTTALBBACE1 | |
| SCHEMBL5717548 | 0.82 | TYMS (0.46) | ALDH1A1HTTNPC1PPM1BNT5E | |
| SCHEMBL4130043 | 0.82 | TYMS (0.46) | ALDH1A1HTTNPC1PPM1BNT5E | |
| SCHEMBL13871560 | 0.82 | TYMS (0.46) | ALDH1A1HTTNPC1PPM1BNT5E | |
| SCHEMBL19657159 | 0.80 | ALB (0.55) | DCKALDH1A1HTTALBPOLG | |
| SCHEMBL5717526 | 0.80 | ALB (0.55) | DCKALDH1A1HTTALBPOLG | |
| SCHEMBL2580898 | 0.80 | ALB (0.55) | DCKALDH1A1HTTALBPOLG | |
| SCHEMBL2580896 | 0.80 | ALB (0.55) | DCKALDH1A1HTTALBPOLG | |
| SCHEMBL11598911 | 0.79 | MEN1 (0.55) | DCKALDH1A1HTTALB | |
| SCHEMBL23750658 | 0.78 | P2RY6 (0.45) | ALDH1A1HTTNPC1PPM1BNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6896900-B2 | β-L-2'-deoxy-nucleosides for the treatment of HIV infection | EMORY UNIVERSITY (US) | 2005-05-24 | — | — | US | disclosed |