Indene

Indene

SCHEMBL6285027

C1=Cc2ccccc2C1.N

nearest known ligand 0.53

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
PARP1 P09874 1/20 0.41
TSHR P16473 1/20 0.33
MAOB P27338 2/20 0.31
TRPA1 O75762 1/20 0.31
IDO1 P14902 2/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indene SCHEMBL29492590 1.00 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL27842909 1.00 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL27564191 0.97 CA1 (0.52) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL8336138 0.97 CA1 (0.55) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL8617 0.97
Indene SCHEMBL29350094 0.97
Indene SCHEMBL23071394 0.95 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL1054910 0.95 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL8971559 0.95 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL7153004 0.95 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079791-A Racemization method of chiral indene amine 2026-05-26 CN claimed
CN-122079792-A Synthesis method of chiral indene amine 2026-05-26 CN claimed
CN-119798092-A Imine intermediate of indenofloxacin, cis-indene intermediate and preparation method thereof 宁夏格瑞精细化工有限公司 2025-04-11 CN claimed
CN-119661374-A Method for preparing (1R, 2S) -2, 6-dimethyl-1-indene amine by using chiral amino acid resolving agent 中国科学院大连化学物理研究所 2025-03-21 CN claimed
CN-119462395-A Synthesis method of chiral indene amine 中国科学院大连化学物理研究所 2025-02-18 CN claimed
CN-118878424-A Synthesis method of indene fluorooxamide intermediate indene amine 安徽省化工研究院 2024-11-01 CN claimed
EP-3429352-B1 PROCESS FOR CONVERTING S-ENANTIOMER TO ITS RACEMIC FORM FMC CORP (US) 2021-05-05 EP claimed
CN-108777958-B Process for converting the S-enantiomer into its racemic form FMC有限公司 2021-03-12 CN claimed
US-10570086-B2 Process for converting S-enantiomer to its racemic form FMC CORPORATION (US) 2020-02-25 US claimed
EP-3560911-A1 PROCESS FOR CONVERTING S-ENANTIOMER TO ITS RACEMIC FORM FMC Corporation (US) 2019-10-30 EP claimed
CN-108586455-A A kind of preparation method of 8- alkenyls Indoli zine derivatives 淮阴师范学院 2018-09-28 CN claimed
CN-106478429-B A kind of method of the trans indenes amine alcohol of synthesis of chiral 上海瀚鸿科技股份有限公司 2018-02-13 CN claimed
WO-2017160933-A1 PROCESS FOR CONVERTING S-ENANTIOMER TO ITS RACEMIC FORM FMC CORPORATION (US) 2017-09-21 WO claimed
CN-106480119-A A kind of preparation method of chirality indenes amine 陈永军 2017-03-08 CN claimed
CN-103113306-A Synthesis method of 2,3-benzopyrrole compound NPS-1577 UNIV TONGJI 2013-05-22 CN claimed
CN-100473654-C S-type 4-substituted hydroxypyranoindolidine compound and its derivative and preparation method thereof TANABE SEIYAKU CO (JP) 2009-04-01 CN claimed
CN-100429203-C Dyeing compsn. for kerationous fibres comprising particular dicationic diazo dye OREAL (FR) 2008-10-29 CN claimed
CN-1294123-C Composition for dyeing keratinous fibres comprising a particular dicationic diazo dye OREAL (FR) 2007-01-10 CN claimed
CN-1551756-A Composition for dyeing keratinous fibres comprising a particular dicationic diazo dye �ź㴫 2004-12-01 CN claimed
CN-1541207-A Dyeing compsn. for kerationous fibres comprising particular dicationic diazo dye �ź㴫 2004-10-27 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570086-B2 Process for converting S-enantiomer to its racemic form ADRM1, SULT1E1, CYP3A4 CA1 4473/4885CA2 4103/4885CYP2D6 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.