Phthalimide

Phthalimide

SCHEMBL6285181

C=C(C)C(=O)NC.O=C1NC(=O)c2ccccc21

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.52
CASP3 P42574 4/20 0.46
CASP2 P42575 1/20 0.46
CASP7 P55210 1/20 0.46
CASP6 P55212 1/20 0.46
CASP8 Q14790 1/20 0.46
ALDH1A1 P00352 6/20 0.44
KDM4E B2RXH2 4/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
TGM2 P21980 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
IDO1 P14902 1/20 0.38
GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL8092178 0.83 GSK3B (0.62) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL34465463 0.82 GSK3B (0.60) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL1132405 0.79 GSK3B (0.75) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL27709410 0.79 GSK3B (0.56) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL4318901 0.77 GSK3B (0.71) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL7624685 0.76 GSK3B (0.52) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL10544624 0.75 GSK3B (0.68) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL11492689 0.75 GSK3B (0.68) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL28322033 0.73 GSK3B (0.71) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL15488735 0.72 GSK3B (0.79) GSK3BCASP3CASP2CASP7CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916862-B2 Process for the preparation of pigment dispersion, pigment dispersion obtained by the same, ink jet recording ink comprising the same, and recording method and recorded material using the same SEIKO EPSON CORPORATION (JP) 2005-07-12 US disclosed
EP-1245652-A1 Aqueous ink for inkjet printing Kao Corporation (JP) 2002-10-02 EP disclosed
US-20020075369-A1 Process for the preparation of pigment dispersion, pigment dispersion obtained by the same, ink jet recording ink comprising the same, and recording method and recorded material using the same SEIKO EPSON CORPORATION 2002-06-20 US disclosed
EP-1146090-A2 Process for the preparation of pigment dispersion, pigment dispersion obtained by the same, ink jet recording ink comprising the same, and recording method and recording material using the same SEIKO EPSON CORPORATION (JP) 2001-10-17 EP disclosed
US-5852074-A Aqueous ink for inkjet printing KAO CORPORATION (JP) 1998-12-22 US disclosed
EP-0791610-A2 Aqueus ink for inkjet printing KAO CORPORATION (JP) 1997-08-27 EP disclosed