SCHEMBL6285461

SCHEMBL6285461

COC(=O)c1ccc(OC(C)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
KMT2A Q03164 3/20 0.61
MEN1 O00255 2/20 0.61
MAPT P10636 4/20 0.56
SMN1; SMN2 Q16637 1/20 0.54
TDP1 Q9NUW8 1/20 0.53
CA12 O43570 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
PARP10 Q53GL7 1/20 0.52
STS P08842 1/20 0.51
TSHR P16473 2/20 0.50
RAB9A P51151 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9973023 0.89 KMT2A (0.51) CA1CA2KMT2AMEN1MAPT
SCHEMBL6548631 0.86 CA1 (0.64) CA1CA2KMT2AMEN1MAPT
SCHEMBL1854840 0.86 KMT2A (0.66) CA1CA2KMT2AMEN1MAPT
SCHEMBL7196748 0.86 KMT2A (0.55) CA1CA2KMT2AMEN1MAPT
Methylparaben SCHEMBL165373 0.85 CA1 (0.61) CA1CA2KMT2AMEN1MAPT
SCHEMBL10945824 0.85 PARP10 (0.52) CA1CA2KMT2AMEN1MAPT
SCHEMBL24943239 0.83 CA1 (0.60) CA1CA2KMT2AMEN1MAPT
SCHEMBL6616955 0.83 CA1 (0.60) CA1CA2KMT2AMEN1MAPT
SCHEMBL10591230 0.82 ELANE (0.57) CA1CA2KMT2AMEN1MAPT
SCHEMBL4261434 0.81 MEN1 (0.71) CA1CA2KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6846900-B2 POLYVALENT CARBOXYLIC ACID ESTER, PROCESS FOR PRODUCING THE CARBOXYLIC ACID ESTER, PLASTIC LENS COMPOSITION USING THE CARBOXYLIC ESTER, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION AND PROCESS FOR PRODUCING THE PLASTIC LENS SHOWA DENKO K.K. (JP) 2005-01-25 US disclosed
US-20030144447-A1 Novel polyvalent carboxylic acid ester and their use in plastic lens compositions SHOW A DENKO K.K. (JP) 2003-07-31 US disclosed
EP-0922726-B1 BIAXIALLY ORIENTED POLYETHYLENE NAPHTHALATE COPOLYMER FILM TEIJIN LTD (JP) 2003-03-26 EP disclosed
WO-2002079140-A1 NOVEL POLYVALENT CARBOXYLIC ACID ESTERS AND THEIR USE IN PLASTIC LENS COMPOSITIONS SHOWA DENKO K. K. (JP) 2002-10-10 WO disclosed
US-6048627-A PHOTOGRAPHY BASE FILM, FILMS FOR X-RAYS AND PHOTOENGRAVING TEIJIN LIMITED (JP) 2000-04-11 US disclosed
EP-0922726-A1 BIAXIALLY ORIENTED POLYETHYLENE NAPHTHALATE COPOLYMER FILM TEIJIN LIMITED (JP) 1999-06-16 EP disclosed
EP-0679672-B1 Process for the preparation of modified polybutylene terephthalate resin POLYPLASTICS CO (JP) 1998-07-01 EP disclosed
EP-0517511-B1 Process for the preparation of polyester, and its composition POLYPLASTICS CO (JP) 1997-11-05 EP disclosed
EP-0683201-A1 Process for the preparation of modified polybutylene terephthalate resin POLYPLASTICS CO. LTD. (JP) 1995-11-22 EP disclosed
EP-0679672-A1 Process for the preparation of modified polybutylene terephthalate resin POLYPLASTICS CO. LTD. (JP) 1995-11-02 EP disclosed
EP-0678552-A1 Process for the preparation of modified polybutylene terephthalate resin POLYPLASTICS CO. LTD. (JP) 1995-10-25 EP disclosed
US-5302690-A Catalytic transesterification POLYPLASTICS CO., LTD. (JP) 1994-04-12 US disclosed
US-5300332-A Modified with an aromatic sulfonic acid compound; tensile strength POLYPLASTICS CO., LTD. (JP) 1994-04-05 US disclosed
EP-0556050-A1 Modified polyester and method of manufacturing same POLYPLASTICS CO. LTD. (JP) 1993-08-18 EP disclosed
EP-0517511-A2 Process for the preparation of polyester, and its composition POLYPLASTICS CO. LTD. (JP) 1992-12-09 EP disclosed
US-4314052-A Polyester which is soluble or dispersible in water, a process for its preparation and its use as a levelling auxiliary, levelling auxiliaries and processes for uniform dyeing CASSELLA AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed
US-4304569-A Formulation for brightening synthetic fibers and its preparation and use CASSELLA AG. (DE) 1981-12-08 US disclosed
US-4087479-A A POLYESTER AND A POLYEPOXIDE COMPOUND NIPPON ESTER CO., LTD. (JA) 1978-05-02 US disclosed
US-3991034-A POWDER PAINT NIPPON ESTER CO., LTD. (JA) 1976-11-09 US disclosed
US-3954901-A HEXAKIS(ALKOXYMETHYL)MELAMINE HARDENER NIPPON ESTER CO., LTD. (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144447-A1 Novel polyvalent carboxylic acid ester and their use in plastic lens compositions VCL, VIM, CRYAA CA1 1241/4885CA2 1306/4885KMT2A 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.