SCHEMBL6285727

SCHEMBL6285727

CC1([Zr](Cl)(Cl)C2(C)C(c3ccccc3)=Cc3ccccc32)C(c2ccccc2)=Cc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2357071 0.77
SCHEMBL7063677 0.76 LPL (0.31)
SCHEMBL6923405 0.76 ESR1 (0.32) ESR1ESR2
SCHEMBL28814696 0.73 ESR1 (0.42) ESR1ESR2
SCHEMBL6289887 0.72 ESR1 (0.39) ESR1ESR2
SCHEMBL16321979 0.71 ESR1 (0.41) ESR1ESR2
SCHEMBL7026730 0.71 ESR1 (0.41) ESR1ESR2
Hydrochloric Acid SCHEMBL6289884 0.70 ESR1 (0.43) ESR1ESR2
Hydrochloric Acid SCHEMBL6285729 0.70 ESR1 (0.40) ESR1ESR2
Hydrochloric Acid SCHEMBL6285717 0.70 ESR1 (0.40) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6960550-B2 Catalyst systems for high melting thermoplastic elastomeric α-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2005-11-01 US claimed
US-6960550-B2 Catalyst systems for high melting thermoplastic elastomeric α-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2005-11-01 US disclosed
US-20030195308-A1 Catalyst systems for high melting thermoplastic elastomeric alpha-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-10-16 US disclosed
US-6559262-B1 An elastomeric amorphous-crystalline blocks copolymer of at least one alpha olefin monomor with ethylene having less than 10 mole % ethylene units, said ethylene is incorporated randomly between the olefin units in the polymer chain with a THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY 2003-05-06 US disclosed
US-6518378-B2 Using an unbridged cyclopentadienyl metallocene catalyst capable of interconverting between states with different copolymerization characteristics THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-02-11 US disclosed
US-6479685-B2 POLYMERIZING ETHYLENE AND ANOTHER ALPHA-OLEFIN IN THE PRESENCE OF AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST COMPONENT AND A CO-CATALYST THE BOARD OF TRUSTEES OF THE LELAND STANDARD JUNIOR UNIVERSITY 2002-11-12 US disclosed
US-20010049425-A1 High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis BP CORPORATION NORTH AMERICA INC. 2001-12-06 US disclosed
US-20010034426-A1 High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis BP CORPORATION NORTH AMERICA INC. 2001-10-25 US disclosed
US-6169151-B1 MADE BY POLYMERIZING ETHYLENE AND ALPHA-OLEFIN(S) USING AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST AND COCATALYST; CRYSTALLIZABLE ELASTOMERIC COPOLYMER PRODUCT HAS HIGHER MELTING POINT, NARROW COMPOSITION DISTRIBUTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2001-01-02 US disclosed
US-6160064-A POLYMERIZING MONOMERS IN PRESENCE OF CATALYST SYSTEM COMPRISING UNBRIDGED FLUXIONAL METALLOCENE AND COCATALYST, INTRODUCING ETHYLENE INTO SYSTEM TO INDUCE POLYMERIZATION RATE ENHANCEMENT/ELASTOMERIC PROPERTY ENHANCING EFFECTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2000-12-12 US disclosed