SCHEMBL6286361

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6286783	0.85	KCNH2 (0.59)	MAOBKCNH2POLA1
	SCHEMBL6281423	0.77	KCNH2 (0.53)	KCNH2POLA1
	SCHEMBL6286406	0.76	MAOB (0.50)	MAOBMAOAL3MBTL1CA12CA1
	SCHEMBL6703119	0.75	F2 (0.47)	KCNH2POLA1
	SCHEMBL6285021	0.74	L3MBTL1 (0.48)	MAOBMAOAL3MBTL1CA12CA1
	SCHEMBL6693496	0.73	MAPT (0.60)	KCNH2POLA1
	SCHEMBL6283816	0.72	KCNH2 (0.59)	KCNH2POLA1
	SCHEMBL6286617	0.71	KCNH2 (0.58)	KCNH2POLA1
	SCHEMBL6692334	0.71	POLA1 (0.52)	KCNH2POLA1
	SCHEMBL6793742	0.70	POLA1 (0.57)	KCNH2POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.