Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 11/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5289923 | 0.75 | HTR1B (0.77) | HTR1BKCNA3HTR1DKMT2AMEN1 | |
| SCHEMBL7972597 | 0.73 | HTR1B (0.51) | HTR1BKCNA3HTR1DKMT2AMEN1 | |
| SCHEMBL2177350 | 0.73 | HTR1B (0.78) | HTR1BKCNA3HTR1DKMT2ATDP1 | |
| SCHEMBL9770352 | 0.73 | KCNA3 (0.81) | HTR1BKCNA3HTR1DKMT2AMEN1 | |
| SCHEMBL8981682 | 0.73 | KMT2A (0.69) | HTR1BKCNA3HTR1DKMT2AALDH1A1 | |
| SCHEMBL2116954 | 0.72 | HTR1B (0.70) | HTR1BKCNA3HTR1DSLC6A4HRH1 | |
| SCHEMBL30209610 | 0.72 | HTR1B (0.70) | HTR1BKCNA3HTR1DSLC6A4HRH1 | |
| SCHEMBL16902853 | 0.71 | KCNA3 (0.79) | HTR1BKCNA3HTR1DKMT2AMEN1 | |
| SCHEMBL16902854 | 0.71 | KCNA3 (0.79) | HTR1BKCNA3HTR1DKMT2AMEN1 | |
| SCHEMBL16902840 | 0.71 | KCNA3 (0.79) | HTR1BKCNA3HTR1DKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951918-B2 | Peptidic procollagen C-proteinase inhibitors | SYNTEX (U.S.A.) LLC (US) | 2005-10-04 | — | — | US | disclosed |
| US-6426402-B1 | RESPIRATORY SYSTEM DISORDERS; RHEUMATIC DISEASES | SYNTEX (U.S.A.) LLC | 2002-07-30 | — | — | US | disclosed |