Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL9645942 | 0.96 | MEN1 (0.50) | MEN1KMT2ATSHRCA5ACA5B | |
| Ethylenediamine SCHEMBL11236232 | 0.92 | — | — | |
| Ethylenediamine SCHEMBL3613718 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Ethylenediamine SCHEMBL8580116 | 0.92 | — | — | |
| Ethylenediamine SCHEMBL8214212 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Ethylenediamine SCHEMBL3746450 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Ethylenediamine SCHEMBL3746452 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Ethylenediamine SCHEMBL11443647 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Ethylenediamine SCHEMBL2023673 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Ethylenediamine SCHEMBL11039278 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050279030-A1 | CMP formulations | SAINT-GOBAIN CERAMICS & PLASTICS, INC. (US) | 2005-12-22 | — | — | US | disclosed |
| US-6945851-B2 | CMP formulations | SAINT-GOBAIN CERAMICS & PLASTICS, INC. (US) | 2005-09-20 | — | — | US | disclosed |
| US-20050020187-A1 | CMP formulations | SAINT-GOBAIN CERAMICS & PLASTICS, INC. | 2005-01-27 | — | — | US | disclosed |
| EP-1476518-A1 | CMP FORMULATIONS FOR THE USE ON NICKEL-PHOSPHORUS ALLOYS | Saint-Gobain Ceramics and Plastics, Inc. (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6755721-B2 | Chemical mechanical polishing of nickel phosphorous alloys | SAINT-GOBAIN CERAMICS AND PLASTICS, INC. | 2004-06-29 | — | — | US | disclosed |
| US-20030171072-A1 | Improved chemical mechanical polishing of nickel phoshorous alloys | SAINT-GOBAIN CERAMICS & PLASTICS, INC. | 2003-09-11 | — | — | US | disclosed |
| WO-2003072671-A1 | CMP FORMULATIONS FOR THE USE ON NICKEL-PHOSPHORUS ALLOYS | SAINT-GOBAIN CERAMICS & PLASTICS, INC. (US) | 2003-09-04 | — | — | WO | disclosed |