Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 6/20 | 0.36 |
| ▸ | MAOB | P27338 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SQLE | Q14534 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287454 | 0.80 | CHRNA7 (0.50) | TP53KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL410570 | 0.80 | KDM4E (0.57) | TDP1TP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16952743 | 0.79 | CYP2C19 (0.43) | TDP1TP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30988603 | 0.78 | TDP1 (0.41) | TDP1TP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25560293 | 0.78 | TDP1 (0.38) | TDP1TP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5033484 | 0.78 | TP53 (0.43) | TDP1TP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL412110 | 0.77 | KMT2A (0.50) | TDP1TP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6280406 | 0.76 | TDP1 (0.42) | TDP1TP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1360315 | 0.76 | TP53 (0.39) | TDP1TP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12305040 | 0.76 | L3MBTL1 (0.51) | TP53SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900273-B1 | Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part | HITACHI CHEMICAL CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20040220342-A1 | Low-hygroscopicity low-birefringence resin compositions, molding material, sheet or film obtained therefrom, and optical part | YAMASHITA YUKIHIKO (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1205517-A1 | LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |