SCHEMBL6286657

SCHEMBL6286657

O=C(OCc1ccccc1)c1ccc(OCCO)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.65
SLC6A2 P23975 1/20 0.65
SLC6A3 Q01959 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
LMNA P02545 2/20 0.64
GAA P10253 2/20 0.62
MAPT P10636 4/20 0.56
ALDH1A1 P00352 3/20 0.56
HPGD P15428 1/20 0.56
NR4A1 P22736 1/20 0.55
NR4A2 P43354 1/20 0.55
NR4A3 Q92570 1/20 0.55
RECQL P46063 1/20 0.53
RAB9A P51151 4/20 0.53
MAOB P27338 1/20 0.53
PARP10 Q53GL7 1/20 0.53
MEN1 O00255 1/20 0.51
SRD5A2 P31213 1/20 0.51
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4815672 0.97 KMT2A (0.61) KMT2ASLC6A2SLC6A3TDP1LMNA
SCHEMBL51012 0.92 KMT2A (0.71) KMT2ASLC6A2SLC6A3TDP1LMNA
SCHEMBL25119644 0.92 KMT2A (0.58) KMT2ASLC6A2SLC6A3TDP1LMNA
SCHEMBL25119553 0.92 KMT2A (0.58) KMT2ASLC6A2SLC6A3TDP1LMNA
SCHEMBL28369758 0.88 KMT2A (0.70) KMT2ASLC6A2SLC6A3TDP1LMNA
SCHEMBL8673498 0.88 KMT2A (0.65) KMT2ASLC6A2SLC6A3TDP1LMNA
SCHEMBL50807 0.87 KMT2A (0.73) KMT2ASLC6A2SLC6A3TDP1LMNA
SCHEMBL13481158 0.87 KMT2A (0.63) KMT2ASLC6A2SLC6A3TDP1LMNA
SCHEMBL20830910 0.87 TSHR (0.65) KMT2ASLC6A2SLC6A3TDP1LMNA
SCHEMBL1242971 0.87 KMT2A (0.63) KMT2ASLC6A2SLC6A3TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023058418-A1 COMPOSITION, AND PHOTOSENSITIVE COMPOSITION 東京応化工業株式会社 2023-04-13 WO disclosed
US-6846900-B2 POLYVALENT CARBOXYLIC ACID ESTER, PROCESS FOR PRODUCING THE CARBOXYLIC ACID ESTER, PLASTIC LENS COMPOSITION USING THE CARBOXYLIC ESTER, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION AND PROCESS FOR PRODUCING THE PLASTIC LENS SHOWA DENKO K.K. (JP) 2005-01-25 US disclosed
US-20030144447-A1 Novel polyvalent carboxylic acid ester and their use in plastic lens compositions SHOW A DENKO K.K. (JP) 2003-07-31 US disclosed
WO-2002079140-A1 NOVEL POLYVALENT CARBOXYLIC ACID ESTERS AND THEIR USE IN PLASTIC LENS COMPOSITIONS SHOWA DENKO K. K. (JP) 2002-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144447-A1 Novel polyvalent carboxylic acid ester and their use in plastic lens compositions VCL, VIM, CRYAA KMT2A 334/4885SLC6A2 4864/4885SLC6A3 4751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.