Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 8/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007346 | 0.90 | AVPR1B (0.54) | AVPR1BF2AVPR1APLGBMP1 | |
| SCHEMBL1509781 | 0.90 | AVPR1B (0.54) | AVPR1BF2AVPR1APLGBMP1 | |
| SCHEMBL1509780 | 0.90 | AVPR1B (0.54) | AVPR1BF2AVPR1APLGBMP1 | |
| SCHEMBL7898282 | 0.90 | AVPR1B (0.54) | AVPR1BF2AVPR1APLGBMP1 | |
| SCHEMBL9329697 | 0.83 | AVPR1B (0.52) | AVPR1BF2AVPR1APLGBMP1 | |
| SCHEMBL6435876 | 0.80 | AVPR1B (0.69) | AVPR1BF2AVPR1APLG | |
| SCHEMBL2873083 | 0.79 | AVPR1B (0.48) | AVPR1BF2AVPR1APLGBMP1 | |
| SCHEMBL29816989 | 0.79 | AVPR1B (0.48) | AVPR1BF2AVPR1APLGBMP1 | |
| SCHEMBL1738663 | 0.79 | AVPR1B (0.52) | AVPR1BAVPR1APLGBMP1 | |
| SCHEMBL3501647 | 0.78 | AVPR1B (0.47) | AVPR1BF2AVPR1APLGBMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | MPL, THPO, TEK | AVPR1B 1073/4885F2 133/4885AVPR1A 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.