Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 16/20 | 0.75 |
| ▸ | THRA | P10827 | 4/20 | 0.75 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642033 | 0.85 | THRB (1.00) | THRBTHRA | |
| SCHEMBL6213522 | 0.82 | THRB (0.90) | THRBTHRA | |
| SCHEMBL6213056 | 0.80 | THRB (1.00) | THRBTHRA | |
| SCHEMBL6216224 | 0.80 | THRB (0.80) | THRBTHRA | |
| SCHEMBL6213947 | 0.76 | THRB (0.79) | THRBTHRA | |
| SCHEMBL6216237 | 0.75 | THRB (0.81) | THRBTHRA | |
| SCHEMBL6215414 | 0.71 | THRB (0.79) | THRBTHRA | |
| SCHEMBL6217508 | 0.69 | THRB (0.72) | THRBTHRA | |
| SCHEMBL6214172 | 0.68 | THRB (0.69) | THRBTHRA | |
| SCHEMBL6218117 | 0.67 | THRB (0.61) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930107-B2 | 6-azauracil derivatives as thyroid receptor ligands | PFIZER INC. (US) | 2005-08-16 | — | — | US | claimed |