SCHEMBL6286848

SCHEMBL6286848

CN(C)C1CCc2c(ccc(O)c2O)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.67
DRD1 P21728 2/20 0.67
DRD4 P21917 2/20 0.55
DRD3 P35462 2/20 0.55
CHRM3 P20309 1/20 0.54
HTR1A P08908 5/20 0.50
HTR7 P34969 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7204012 0.98 DRD2 (0.65) DRD2DRD1DRD4DRD3CHRM3
SCHEMBL7788774 0.80 DRD2 (1.00) DRD2DRD1DRD4DRD3HTR1A
SCHEMBL7362530 0.80 DRD2 (1.00) DRD2DRD1DRD4DRD3HTR1A
SCHEMBL339581 0.80 CHRM3 (0.77) DRD2DRD1DRD4DRD3CHRM3
SCHEMBL3312525 0.80 CHRM3 (0.77) DRD2DRD1DRD4DRD3CHRM3
SCHEMBL3313069 0.80 CHRM3 (0.77) DRD2DRD1DRD4DRD3CHRM3
SCHEMBL10881893 0.79 DRD2 (0.48) DRD2DRD1DRD4DRD3CHRM3
SCHEMBL14283972 0.79 CHRM3 (0.65) DRD2DRD1DRD4DRD3CHRM3
Hydrochloric Acid SCHEMBL10879409 0.78 DRD2 (0.47) DRD2DRD1DRD4DRD3CHRM3
SCHEMBL10886632 0.77 DRD2 (0.49) DRD2DRD1DRD4DRD3CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0170193-B1 FEEDSTUFF ADDITIVE FOR THE GROWTH PROMOTING OF AGRICULTURAL USEFUL ANIMALS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1991-12-27 EP claimed
EP-0170193-A2 Feedstuff additive for the growth promoting of agricultural useful animals BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1986-02-05 EP claimed
US-6953813-B1 2-Aminotetralin derivatives for the therapy of glaucoma CHIESI FARMACEUTICI S.P.A. (IT) 2005-10-11 US disclosed
EP-1200079-B1 2-AMINOTETRALIN DERIVATIVES FOR THE THERAPY OF GLAUCOMA CHIESI FARMA SPA (IT) 2003-09-24 EP disclosed
US-5135929-A Administering imidazotriazines BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1992-08-04 US disclosed
US-4853402-A 2-SUBSTITUTED-2-IMIDAZOLINES BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1989-08-01 US disclosed
EP-0170193-A2 Feedstuff additive for the growth promoting of agricultural useful animals BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1986-02-05 EP disclosed