Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284860 | 0.77 | — | — | |
| SCHEMBL5588331 | 0.76 | ACHE (0.42) | ACHEBACE1HPGDNPC1MAPK1 | |
| SCHEMBL27516481 | 0.76 | ACHE (0.42) | ACHEBACE1HPGDNPC1MAPK1 | |
| SCHEMBL6053830 | 0.69 | ACHE (0.37) | ACHEBACE1HPGDNPC1MAPK1 | |
| SCHEMBL27794725 | 0.67 | HRH3 (0.33) | ACHEBACE1HPGDNPC1MAPK1 | |
| SCHEMBL1027608 | 0.67 | ACHE (0.39) | ACHEBACE1HPGDNPC1MAPK1 | |
| SCHEMBL6361888 | 0.65 | STAT3 (0.58) | ACHEBACE1HPGDMAPK1ALDH1A1 | |
| SCHEMBL6053940 | 0.65 | TSHR (0.35) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL4663343 | 0.65 | SKP2 (0.37) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL27949031 | 0.63 | HPGD (0.39) | HPGDNPC1MAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930193-B | Class of metallocenes and method of producing polyethylene | UNIVATION TECH LLC | 2011-03-23 | — | — | CN | disclosed |
| CN-1930193-A | Class of metallocenes and method of producing polyethylene | UNIVATION TECH LLC (US) | 2007-03-14 | — | — | CN | disclosed |
| US-6911508-B2 | Class of metallocenes and method of producing polyethylene | UNIVATION TECHNOLOGIES, LLC (US) | 2005-06-28 | — | — | US | disclosed |
| US-20040249096-A1 | Class of metallocenes and method of producing polyethylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-09 | — | — | US | disclosed |