Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.43 |
| ▸ | IAPP | P10997 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12225988 | 0.90 | PTGER4 (0.58) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL27442369 | 0.90 | PTGER4 (0.62) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL11038460 | 0.81 | PTGER1 (0.49) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL1261128 | 0.79 | PTGER4 (0.77) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL31212507 | 0.79 | PTGER4 (0.77) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL29277857 | 0.79 | IAPP (0.51) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL6053663 | 0.78 | PTGER4 (0.81) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL1567197 | 0.78 | PTGER4 (0.60) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL6206188 | 0.76 | PTGER4 (0.58) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL8962348 | 0.75 | ALDH1A1 (0.77) | KMT2AALDH1A1FFAR1CNR2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911468-B2 | Tyrosine phosphatase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | PTPRC, PTPN1, PTPRM | PTGER4 4389/4885PTGER3 4460/4885PTGER1 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.