SCHEMBL628771

SCHEMBL628771

NC(=O)Cc1ccc2ccccc2c1C=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.53
MAPT P10636 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
MTNR1A P48039 2/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
GLA P06280 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
P2RX3 P56373 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6754145 0.85 TDP1 (0.59) ERN1MAPTL3MBTL1NPC1RAB9A
SCHEMBL28055018 0.84 ERN1 (0.53) ERN1MAPTL3MBTL1NPC1RAB9A
SCHEMBL2646726 0.81 ERN1 (0.61) ERN1MAPTL3MBTL1NPC1RAB9A
SCHEMBL5841524 0.80 ERN1 (0.55) ERN1MAPTL3MBTL1NPC1RAB9A
SCHEMBL3268984 0.78 ERN1 (0.56) ERN1MAPTL3MBTL1NPC1RAB9A
SCHEMBL6754178 0.77 ERN1 (0.56) ERN1MAPTL3MBTL1NPC1RAB9A
SCHEMBL5841800 0.77 ERN1 (0.51) ERN1MAPTL3MBTL1NPC1RAB9A
SCHEMBL7477565 0.77 POLB (0.47) MAPTNPC1RAB9ASMN1; SMN2GAA
SCHEMBL27480626 0.77 TSHR (0.46) L3MBTL1RAB9AGAATDP1CYP1A2
SCHEMBL6753106 0.76 ERN1 (0.51) ERN1MAPTL3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2036984-B1 Reversion of the negative selective effect of negative marker proteins as selection procedure BASF PLANT SCIENCE GMBH (DE) 2012-02-22 EP claimed
EP-2036984-A2 Reversion of the negative selective effect of negative marker proteins as selection procedure BASF Plant Science GmbH (DE) 2009-03-18 EP claimed
EP-1527183-B1 NOVEL SELECTION METHOD BASF PLANT SCIENCE GMBH (DE) 2008-08-20 EP claimed
US-20060218658-A1 Novel selection method BASF PLANT SCIENCE GMBH (DE) 2006-09-28 US claimed
US-20150368663-A1 METHOD FOR ISOLATION OF TRANSCRIPTION TERMINATION SEQUENCES BASF PLANT SCIENCE GMBH (DE) 2015-12-24 US disclosed
US-9133466-B2 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2015-09-15 US disclosed
EP-2074219-B1 NUCLEIC ACID SEQUENCES FOR REGULATION OF EMBRYO-SPECIFIC EXPRESSION IN MONOCOTYLEDONOUS PLANTS BASF PLANT SCIENCE GMBH (DE) 2013-11-20 EP disclosed
US-20130236954-A1 Method for Isolation of Transcription Termination Sequences BASF PLANT SCIENCE GMBH (DE) 2013-09-12 US disclosed
US-8465915-B2 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2013-06-18 US disclosed
EP-2166104-B1 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2013-06-12 EP disclosed
EP-2166103-B1 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2013-05-22 EP disclosed
EP-2163635-B1 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2013-05-22 EP disclosed
US-20070243543-A1 Method for Isolation of Transcription Termination Sequences BASF PLANT SCIENCE GMBH (DE) 2007-10-18 US disclosed
WO-2006133983-A1 STARCHY-ENDOSPERM AND/OR GERMINATING EMBRYO-SPECIFIC EXPRESSION IN MONO-COTYLEDONOUS PLANTS BASF PLANT SCIENCE GMBH (DE) 2006-12-21 WO disclosed
EP-1727907-A1 POST HARVEST CONTROL OF GENETICALLY MODIFIED CROP GROWTH EMPLOYING D-AMINO ACID COMPOUNDS BASF Plant Science GmbH (DE) 2006-12-06 EP disclosed
EP-1727906-A1 IMPROVED CONSTRUCTS FOR MARKER EXCISION BASED ON DUAL-FUNCTION SELECTION MARKER BASF Plant Science GmbH (DE) 2006-12-06 EP disclosed
WO-2005090581-A1 IMPROVED CONSTRUCTS FOR MARKER EXCISION BASED ON DUAL-FUNCTION SELECTION MARKER BASF PLANT SCIENCE GMBH (DE) 2005-09-29 WO disclosed
WO-2005090582-A1 POST HARVEST CONTROL OF GENETICALLY MODIFIED CROP GROWTH EMPLOYING D-AMINO ACID COMPOUNDS BASF PLANT SCIENCE GMBH (DE) 2005-09-29 WO disclosed
EP-1527183-A2 NOVEL SELECTION METHOD BASF Plant Science GmbH (DE) 2005-05-04 EP disclosed
WO-2004013333-A2 INVERSION OF THE NEGATIVE-SELECTIVE EFFECT OF NEGATIVE MARKER PROTEINS USING SELECTION METHODS BASF PLANT SCIENCE GMBH (DE) 2004-02-12 WO disclosed