Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287685 | 0.86 | HDAC1 (0.52) | HRH3L3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6287783 | 0.86 | HDAC8 (0.61) | MAPTSMN1; SMN2HDAC1LMNAHTT | |
| SCHEMBL8280156 | 0.85 | MMP9 (0.56) | L3MBTL1ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL6287655 | 0.84 | HDAC1 (0.50) | HRH3ALDH1A1MAPTSMN1; SMN2HDAC1 | |
| SCHEMBL6284142 | 0.84 | HDAC1 (0.50) | HRH3MAPTSMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL6288043 | 0.83 | HDAC8 (0.49) | HRH3L3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6290992 | 0.83 | HDAC8 (0.54) | HRH3MAPTSMN1; SMN2HDAC1MEN1 | |
| SCHEMBL7038483 | 0.83 | HDAC1 (0.49) | HRH3L3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6291018 | 0.83 | CTSC (0.48) | HRH3L3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25802387 | 0.83 | HRH3 (0.66) | HRH3L3MBTL1ALDH1A1MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |