Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 15/20 | 0.86 |
| ▸ | MMP2 | P08253 | 13/20 | 0.86 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.67 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.67 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301154 | 0.93 | MMP9 (1.00) | MMP9MMP2NR3C1KCNA5ADAM17 | |
| SCHEMBL14602247 | 0.88 | MMP9 (1.00) | MMP9MMP2NR3C1KCNA5MEN1 | |
| SCHEMBL7386419 | 0.88 | MMP9 (1.00) | MMP9MMP2NR3C1KCNA5MEN1 | |
| SCHEMBL5191094 | 0.87 | MMP9 (0.89) | MMP9MMP2KCNA5ADAM17MEN1 | |
| SCHEMBL6720186 | 0.87 | MMP9 (0.89) | MMP9MMP2KCNA5ADAM17MEN1 | |
| SCHEMBL14602277 | 0.87 | MMP9 (0.84) | MMP9MMP2NR3C1KCNA5ADAM17 | |
| SCHEMBL12299558 | 0.87 | MMP9 (1.00) | MMP9MMP2NR3C1KCNA5ADAM17 | |
| SCHEMBL8446523 | 0.87 | MMP9 (0.92) | MMP9MMP2NR3C1KCNA5ADAM17 | |
| SCHEMBL3154764 | 0.86 | MMP9 (0.88) | MMP9MMP2NR3C1KCNA5ADAM17 | |
| SCHEMBL3154749 | 0.86 | MMP9 (0.88) | MMP9MMP2NR3C1KCNA5ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838483-B2 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | SHIONOGI & CO., LTD. (JP) | 2005-01-04 | — | — | US | claimed |