⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628810 | 1.00 | — | — | |
| SCHEMBL9068327 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL14813509 | 0.98 | CA1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL1068300 | 0.98 | CA1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL1068296 | 0.98 | CA1 (0.45) | — | |
| SCHEMBL10402326 | 0.90 | CA1 (0.40) | — | |
| SCHEMBL11776470 | 0.87 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL3649449 | 0.86 | CA1 (0.59) | — | |
| SCHEMBL628944 | 0.86 | CA1 (0.59) | — | |
| SCHEMBL186090 | 0.86 | CA1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098949-A | A kind of new green synthesizing process for preparing perindopril tert-butylamine salt | 上药东英（江苏）药业有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-105613490-A | Attractant for grub imagoes | SHENZHEN BIOGLOBAL AGRICULTURAL SCIENCE CO LTD | 2016-06-01 | — | — | CN | claimed |
| US-12377100-B2 | Toll like receptor modulator compounds | GILEAD SCIENCES, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| CN-116135228-B | Application of hypocrellin 2-amino substituted or ethylenediamine substituted derivative in preparation of antitumor photodynamic medicine | 中国科学院理化技术研究所 | 2025-06-13 | — | — | CN | disclosed |
| CN-115141123-B | Compound, preparation method thereof and application thereof in preparation of dual inhibitors of histone deacetylase and epoxide hydrolase | 沈阳药科大学 | 2024-05-17 | — | — | CN | disclosed |
| US-20230372527-A1 | COMBINATION OF ANTIBODY-DRUG CONJUGATE AND PARP1 SELECTIVE INHIBITOR | ASTRAZENECA UK LIMITED (GB) | 2023-11-23 | — | — | US | disclosed |
| US-20230372527-A1 | COMBINATION OF ANTIBODY-DRUG CONJUGATE AND PARP1 SELECTIVE INHIBITOR | ASTRAZENECA UK LIMITED (GB) | 2023-11-23 | — | — | US | disclosed |
| CN-116135228-A | Application of hypocrellin 2-amino substituted or ethylenediamine substituted derivative in preparation of antitumor photodynamic medicine | 中国科学院理化技术研究所 | 2023-05-19 | — | — | CN | disclosed |
| CN-115666653-A | Antibody-drug conjugates | 斯皮雷亚有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-113387840-B | PD-1/PD-L1 and HDACs double-target inhibitor, preparation method and application | 中国药科大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-115141123-A | Compound, preparation method thereof and application thereof in preparation of histone deacetylase and epoxide hydrolase dual inhibitor | 沈阳药科大学 | 2022-10-04 | — | — | CN | disclosed |
| WO-1996016654-A1 | 2-(2,3,5,6-TETRAFLUORO-4-PYRIDYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-06-06 | — | — | WO | disclosed |
| WO-1996016649-A1 | 2-HETEROCYCLYLOXY AND THIOMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-06-06 | — | — | WO | disclosed |
| WO-1996016951-A1 | SUBSTITUTED 2-ARYLCARBONYLOXYMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-06-06 | — | — | WO | disclosed |
| US-5494925-A | TREATING DEGENERATIVE DISORDERS; PROTEOLYTIC ENZYME INHIBITOR | STERLING WINTHROP INC. (US) | 1996-02-27 | — | — | US | disclosed |
| EP-0668856-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE. | MERCK & CO INC (US) | 1995-11-22 | — | — | EP | disclosed |
| EP-0668856-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5326773-A | Prodrug enzyme inhibitors | MERCK & CO., INC. (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1994010137-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1994-05-11 | — | — | WO | disclosed |
| CN-1043132-A | Dipeptidase derivant with enzyme inhibition | HOECHST AG (DE) | 1990-06-20 | — | — | CN | disclosed |