SCHEMBL6288977

SCHEMBL6288977

OC1(C2CCCN2)CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
SLC6A4 P31645 2/20 0.40
SLC6A3 Q01959 2/20 0.40
TSHR P16473 1/20 0.34
NOS2 P35228 2/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
PKM P14618 1/20 0.31
MET P08581 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20833049 1.00 MAPT (0.41) MAPTSLC6A4SLC6A3TSHRNOS2
SCHEMBL20833461 0.98 MAPT (0.42) MAPTSLC6A4SLC6A3TSHRNOS2
SCHEMBL20208763 0.98 MAPT (0.42) MAPTSLC6A4SLC6A3TSHRNOS2
SCHEMBL20209452 0.98 MAPT (0.42) MAPTSLC6A4SLC6A3TSHRNOS2
SCHEMBL8989809 0.93 MAPT (0.44) MAPTSLC6A4SLC6A3TSHRPKM
SCHEMBL25983920 0.93 MAPT (0.44) MAPTSLC6A4SLC6A3TSHRPKM
SCHEMBL6602812 0.93 MAPT (0.44) MAPTSLC6A4SLC6A3TSHRPKM
SCHEMBL20833502 0.93 MAPT (0.38) MAPTSLC6A4SLC6A3TSHRNOS2
SCHEMBL20832970 0.91 MAPT (0.46) MAPTSLC6A4SLC6A3TSHRMET
SCHEMBL20832968 0.91 MAPT (0.46) MAPTSLC6A4SLC6A3TSHRMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020191252-A1 TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2020-09-24 WO disclosed
WO-2019055951-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2019-03-21 WO disclosed
US-6884893-B1 Method for selectively dissociating cyclic carboxylic acid anhydrides MERCK PATENT GMBH (DE) 2005-04-26 US disclosed
EP-0905132-B1 Benzothiophenes LILLY CO ELI (US) 2004-08-04 EP disclosed
EP-1218349-A2 METHOD FOR SELECTIVELY DISSOCIATING CYCLIC CARBOXYLIC ACID ANHYDRIDES MERCK PATENT GmbH (DE) 2002-07-03 EP disclosed
WO-2001025215-A2 METHOD FOR SELECTIVELY DISSOCIATING CYCLIC CARBOXYLIC ACID ANHYDRIDES MERCK PATENT GMBH (DE) 2001-04-12 WO disclosed
US-6060488-A ANTICARCINOGENIC AGENTS; POSTMENOPAUSAL CANCER OF BREASTS, UTERUS, CERVIX ELI LILLY AND COMPANY (US) 2000-05-09 US disclosed
WO-1999015521-A1 BENZOTHIOPHENES ELI LILLY AND COMPANY (US) 1999-04-01 WO disclosed
EP-0905132-A1 Benzothiophenes ELI LILLY AND COMPANY (US) 1999-03-31 EP disclosed
EP-0720605-A1 AMINOCYCLOHEXYLESTERS AND USES THEREOF UNIVERSITY OF BRITISH COLUMBIA (CA) 1996-07-10 EP disclosed
WO-1995008544-A1 AMINOCYCLOHEXYLESTERS AND USES THEREOF THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1995-03-30 WO disclosed