Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602812 | 1.00 | MAPT (0.44) | MAPTTSHRSLC6A4SLC6A3MET | |
| SCHEMBL25983920 | 1.00 | MAPT (0.44) | MAPTTSHRSLC6A4SLC6A3MET | |
| SCHEMBL25983369 | 0.98 | MAPT (0.46) | MAPTTSHRSLC6A4SLC6A3MET | |
| SCHEMBL20832968 | 0.98 | MAPT (0.46) | MAPTTSHRSLC6A4SLC6A3MET | |
| SCHEMBL20832970 | 0.98 | MAPT (0.46) | MAPTTSHRSLC6A4SLC6A3MET | |
| SCHEMBL20833049 | 0.93 | MAPT (0.41) | MAPTTSHRSLC6A4SLC6A3MET | |
| SCHEMBL20833217 | 0.93 | MAPT (0.46) | MAPTTSHRSLC6A4SLC6A3MET | |
| SCHEMBL20833230 | 0.93 | MAPT (0.46) | MAPTTSHRSLC6A4SLC6A3MET | |
| SCHEMBL6288977 | 0.93 | MAPT (0.41) | MAPTTSHRSLC6A4SLC6A3MET | |
| SCHEMBL9882413 | 0.91 | MAPT (0.38) | MAPTTSHRSLC6A4SLC6A3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720605-A1 | AMINOCYCLOHEXYLESTERS AND USES THEREOF | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008544-A1 | AMINOCYCLOHEXYLESTERS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1995-03-30 | — | — | WO | disclosed |