SCHEMBL6289014

SCHEMBL6289014

CC(=O)Oc1cc[c]c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.46
HTT P42858 3/20 0.45
KDM4E B2RXH2 4/20 0.43
HSD17B10 Q99714 4/20 0.43
PTGS2 P35354 4/20 0.43
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
PTGS1 P23219 2/20 0.43
ESR1 P03372 1/20 0.43
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43
HMGB1 P09429 1/20 0.43
HPGD P15428 1/20 0.43
GGT1 P19440 1/20 0.43
BLM P54132 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
LMNA P02545 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8748364 0.88 MAPK1 (0.42) SLC22A6HTTKDM4EHSD17B10PTGS2
SCHEMBL20591914 0.83 HSD17B10 (0.46) HTTKDM4EHSD17B10ALDH1A1TSHR
SCHEMBL9776453 0.82 KMT2A (0.40) HTTKDM4EHSD17B10ALDH1A1TSHR
SCHEMBL8748472 0.80 KMT2A (0.54) HSD17B10TSHRTDP1ESR1LMNA
SCHEMBL9472079 0.80 ELANE (0.40) KDM4EHSD17B10ALDH1A1TSHRPTGS1
SCHEMBL19732700 0.79 ALDH1A1 (0.40) HSD17B10ALDH1A1TDP1ESR1HPGD
SCHEMBL30002719 0.77 HTT (0.61) SLC22A6HTTKDM4EHSD17B10PTGS2
SCHEMBL4444465 0.77 HTT (0.61) SLC22A6HTTKDM4EHSD17B10PTGS2
SCHEMBL148270 0.76 IDO1 (0.44) HTTKDM4EALDH1A1TSHRTDP1
SCHEMBL7753169 0.76 IDO1 (0.44) HTTKDM4EALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111808045-B Method for synthesizing chiral seven-element cyclic sulfonamide through organic catalysis 中国科学院大连化学物理研究所 2022-07-08 CN claimed
US-6919157-B2 Positive type radiation-sensitive composition and process for producing pattern with the same TORAY INDUSTRIES, INC. (JP) 2005-07-19 US disclosed
US-20030003392-A1 Positive type radiation-sensitive composition and process for processing for producing pattern with the same TORAY INDUSTRIES, INC. (JP) 2003-01-02 US disclosed
EP-1229390-A1 POSITIVE TYPE RADIATION-SENSITIVE COMPOSITION AND PROCESS FOR PRODUCING PATTERN WITH THE SAME TORAY INDUSTRIES, INC. (JP) 2002-08-07 EP disclosed
EP-0866367-A2 Radiation sensitive composition JSR Corporation (JP) 1998-09-23 EP disclosed
EP-0534257-B1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS (JP) 1997-03-12 EP disclosed
EP-0524419-B1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS (JP) 1995-09-06 EP disclosed
US-5391806-A A storage stable chromogens as color-developing agent or stabilizers MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-02-21 US disclosed
US-5306688-A Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-26 US disclosed
US-5270281-A Chromogenic compound MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-12-14 US disclosed
EP-0534257-A1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
EP-0524419-A1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-27 EP disclosed