Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL394250 | 0.89 | KMT2A (0.54) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| Dimethylamine SCHEMBL6289518 | 0.87 | KMT2A (0.54) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL686321 | 0.87 | KMT2A (0.56) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| Hydrochloric Acid SCHEMBL60929 | 0.85 | KMT2A (0.54) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL394058 | 0.80 | MAPT (0.48) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL30112595 | 0.80 | KMT2A (0.48) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| Propiophenone SCHEMBL27783343 | 0.80 | MAPT (0.62) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL8150640 | 0.77 | MAPT (0.45) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL10405142 | 0.77 | LMNA (0.46) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL8756107 | 0.77 | KMT2A (0.42) | KMT2AMAPTSMN1; SMN2MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900250-B2 | Polymerizable composition | TOYO INK MFG. CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20030212162-A1 | Photopolymerization using photoinitiators | TOYO INK MFG. CO., LTD. (JP) | 2003-11-13 | — | — | US | disclosed |