SCHEMBL6289549

SCHEMBL6289549

CNC(C)CN1CCNC1=O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PER2 O15055 4/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 3/20 0.39
ALDH1A1 P00352 3/20 0.39
CRY2 Q49AN0 1/20 0.37
RAB9A P51151 1/20 0.36
MAPT P10636 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
RET P07949 1/20 0.33
KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20773941 0.84 PER2 (0.39) PER2KMT2AMEN1SMN1; SMN2POLB
SCHEMBL6285446 0.82 PER2 (0.38) PER2KMT2AMEN1SMN1; SMN2POLB
SCHEMBL22363007 0.81 PER2 (0.38) PER2KMT2AMEN1SMN1; SMN2POLB
SCHEMBL2373522 0.80 PIK3CD (0.48) PER2KMT2AMEN1SMN1; SMN2POLB
SCHEMBL5251244 0.80 PIK3CD (0.48) PER2KMT2AMEN1SMN1; SMN2POLB
SCHEMBL13804502 0.77 PER2 (0.38) PER2KMT2AMEN1SMN1; SMN2POLB
SCHEMBL6287623 0.77 KMT2A (0.38) PER2KMT2AMEN1SMN1; SMN2POLB
SCHEMBL1742992 0.77 PER2 (0.49) PER2KMT2AMEN1SMN1; SMN2POLB
SCHEMBL10849824 0.77 PER2 (0.42) PER2KMT2AMEN1SMN1; SMN2POLB
SCHEMBL21485041 0.75 TSHR (0.40) PER2KMT2AMEN1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed