SCHEMBL6289575

SCHEMBL6289575

CCCCNCCCOCCCN1CC(C)NC1=O

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
CYP2C19 P33261 3/20 0.31
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 2/20 0.31
CYP2D6 P10635 2/20 0.31
CYP2C9 P11712 1/20 0.31
RECQL P46063 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CNOT7 Q9UIV1 1/20 0.31
KMT2A Q03164 2/20 0.31
PER2 O15055 2/20 0.30
MEN1 O00255 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
GBA1 P04062 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6287473 0.91 CYP1A2 (0.32) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL6289810 0.90 TSHR (0.36) TSHRCYP2C19CYP1A2CYP3A4CYP2D6
SCHEMBL6289661 0.89 PER2 (0.34) TSHRCYP2C19CYP1A2KDM4EALDH1A1
SCHEMBL6286374 0.88 TSHR (0.39) TSHRCYP2C19CYP1A2CYP3A4CYP2D6
SCHEMBL6289585 0.88 GBA1 (0.36) TSHRCYP2C19CYP1A2KDM4EALDH1A1
SCHEMBL6289683 0.86 GBA1 (0.38) TSHRCYP2C19ALDH1A1KMT2APER2
SCHEMBL6284765 0.86 PER2 (0.34) TSHRCYP2C19CYP1A2KDM4EALDH1A1
SCHEMBL6290231 0.85 PER2 (0.32) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL6285626 0.79 PER2 (0.36) PER2
SCHEMBL6283723 0.79 PER2 (0.35) TSHRCYP2C19CYP1A2KMT2APER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed