Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | HPGD | P15428 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619469 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL15131272 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL6888642 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL840117 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL23722477 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL840296 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL6753961 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL11710107 | 0.78 | PDK2 (0.40) | ALDH1A1KDM4ELMNAMAPTHSD17B10 | |
| SCHEMBL2455021 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL4967588 | 0.75 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432938-B1 | RADIAL SHAFT SEAL AND METHOD FOR MAKING SAME | FREUDENBERG CARL KG (DE) | 2005-06-08 | — | — | EP | claimed |
| EP-0266897-A1 | Synthesis of alkylsulfinyl substituted 2-phenylimidazo [4,5-c] pyridines | ELI LILLY AND COMPANY (US) | 1988-05-11 | — | — | EP | disclosed |