SCHEMBL6289851

SCHEMBL6289851

Fc1c(F)c(F)c(C2=Cc3ccccc3C2[Hf](Cl)Cl)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4089941 0.77 CFTR (0.33)
SCHEMBL7195099 0.77
SCHEMBL8584836 0.75 CYP1A2 (0.33)
SCHEMBL7191915 0.73
Hydrochloric Acid SCHEMBL7191911 0.72
Hydrochloric Acid SCHEMBL1980847 0.72
Hydrochloric Acid SCHEMBL6289847 0.72
Hydrochloric Acid SCHEMBL6289846 0.72
Hydrochloric Acid SCHEMBL7195096 0.71
Hydrochloric Acid SCHEMBL392579 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6960550-B2 Catalyst systems for high melting thermoplastic elastomeric α-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2005-11-01 US disclosed
US-20030195308-A1 Catalyst systems for high melting thermoplastic elastomeric alpha-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-10-16 US disclosed
US-6518378-B2 Using an unbridged cyclopentadienyl metallocene catalyst capable of interconverting between states with different copolymerization characteristics THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-02-11 US disclosed
US-20010049425-A1 High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis BP CORPORATION NORTH AMERICA INC. 2001-12-06 US disclosed
US-20010034426-A1 High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis BP CORPORATION NORTH AMERICA INC. 2001-10-25 US disclosed
US-6160064-A POLYMERIZING MONOMERS IN PRESENCE OF CATALYST SYSTEM COMPRISING UNBRIDGED FLUXIONAL METALLOCENE AND COCATALYST, INTRODUCING ETHYLENE INTO SYSTEM TO INDUCE POLYMERIZATION RATE ENHANCEMENT/ELASTOMERIC PROPERTY ENHANCING EFFECTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2000-12-12 US disclosed