SCHEMBL4089941

SCHEMBL4089941

Cl[Hf](Cl)C1C(c2ccccc2)=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.33
GOPC Q9HD26 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8584836 0.96 CYP1A2 (0.33) CFTRGOPC
SCHEMBL8859962 0.82 PTAFR (0.35)
SCHEMBL6290272 0.82 TACR1 (0.32)
SCHEMBL28430085 0.81 CYP11B1 (0.33)
SCHEMBL7937655 0.78 RXRA (0.31)
SCHEMBL7928686 0.78 CNR1 (0.33)
SCHEMBL6289851 0.77
SCHEMBL6285712 0.74 CFTR (0.33) CFTRGOPC
SCHEMBL4089364 0.73
SCHEMBL27448383 0.72 ALDH1A1 (0.33) CFTRGOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0802935-A4 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS UNIV LELAND STANFORD JUNIOR (US) 1998-09-30 EP claimed
EP-0802935-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1997-10-29 EP claimed
WO-1995025757-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-09-28 WO claimed
WO-2009104782-A1 ETHYLENE HOMOPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104783-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104785-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
EP-1157047-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP Corporation North America Inc. (US) 2001-11-28 EP disclosed
WO-2000035975-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. (US) 2000-06-22 WO disclosed