⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146871 | 0.97 | — | — | |
| SCHEMBL11113600 | 0.93 | — | — | |
| SCHEMBL732371 | 0.90 | — | — | |
| SCHEMBL5956778 | 0.90 | — | — | |
| SCHEMBL8736018 | 0.87 | — | — | |
| SCHEMBL5729396 | 0.82 | — | — | |
| SCHEMBL15016076 | 0.79 | — | — | |
| SCHEMBL108892 | 0.78 | — | — | |
| SCHEMBL10903370 | 0.75 | — | — | |
| SCHEMBL384218 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016142918-A1 | PYRAZOLE DERIVATIVES AND RELATIVE USE FOR THE PREPARATION OF 1,3,4-THIADIAZOLES | ISAGRO S.P.A. (IT) | 2016-09-15 | — | — | WO | disclosed |
| US-6867211-B2 | 4-Pyridyl-and 2,4-pyrimidinyl-substituted pyrrole derivatives and their use in pharmacy | MERCKLE GMBH (DE) | 2005-03-15 | — | — | US | disclosed |
| US-20030153558-A1 | 4-Pyridyl-and 2,4-pyrimidinyl-substituted pyrrole derivatives and their use in pharmacy | MERCKLE GMBH (DE) | 2003-08-14 | — | — | US | disclosed |
| EP-0521550-B1 | Vitamin D compound, method of preparing this compound and intermediate therefor | DUPHAR INT RES (NL) | 1996-09-18 | — | — | EP | disclosed |
| EP-0503630-B1 | Cyclohexanetriol derivatives | KURARAY CO (JP) | 1995-12-27 | — | — | EP | disclosed |
| EP-0339046-B1 | LEUKOTRIENE B 4 ANALOGS | UPJOHN CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5334740-A | Cyclohexanetriol derivatives | KURARY CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0521550-A2 | Vitamin D compound, method of preparing this compound and intermediate therefor | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1993-01-07 | — | — | EP | disclosed |
| EP-0503630-A1 | Cyclohexanetriol derivatives | Kuraray Co., Ltd. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5116981-A | Antiinflammatory leukotriene B4 analogs | THE UPJOHN COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0339046-A1 | LEUKOTRIENE B 4? ANALOGS. | UPJOHN CO (US) | 1989-11-02 | — | — | EP | disclosed |
| WO-1988005045-A1 | LEUKOTRIENE B4 ANALOGS | THE UPJOHN COMPANY (US) | 1988-07-14 | — | — | WO | disclosed |
| US-4189606-A | ABOSTIFACIENT | GRUPPO LEPETIT S.P.A. (IT) | 1980-02-19 | — | — | US | disclosed |
| US-4182903-A | ABOSTIFACIENTS | GRUPPO LEPETIT S.P.A. (IT) | 1980-01-08 | — | — | US | disclosed |