SCHEMBL6290127

SCHEMBL6290127

CCCCNC(C)CN1CC(C)NC1=O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PER2 O15055 5/20 0.40
CRY2 Q49AN0 1/20 0.37
MEN1 O00255 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PRKCD Q05655 4/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290072 0.85 PER2 (0.43) PER2CRY2
SCHEMBL6287461 0.80 PER2 (0.36) PER2CRY2
SCHEMBL6287484 0.79 PER2 (0.36) PER2CRY2
SCHEMBL6287648 0.79 PER2 (0.45) PER2CRY2
SCHEMBL6284765 0.75 PER2 (0.34) PER2CRY2MEN1CYP2C19KMT2A
SCHEMBL6289661 0.75 PER2 (0.34) PER2CRY2MEN1CYP2C19KMT2A
SCHEMBL6287623 0.74 KMT2A (0.38) PER2CRY2MEN1CYP2C19KMT2A
SCHEMBL6289585 0.74 GBA1 (0.36) PER2CRY2MEN1CYP2C19KMT2A
SCHEMBL6289683 0.72 GBA1 (0.38) PER2MEN1CYP2C19KMT2AALDH1A1
SCHEMBL6284118 0.72 PER2 (0.36) PER2CRY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed