SCHEMBL629042

SCHEMBL629042

CCCCc1cccc2nc(Cl)[nH]c12

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 8/20 0.41
PARP1 P09874 1/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
DAO P14920 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ADORA3 P0DMS8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31055730 0.94 TLR8 (0.44) TLR8
SCHEMBL29091111 0.81 TLR8 (0.48) TLR8PARP1
SCHEMBL3857633 0.78 PARP1 (0.49) TLR8PARP1
SCHEMBL27696704 0.77 PARP1 (0.48) TLR8PARP1
SCHEMBL16097303 0.77 PARP1 (0.48) TLR8PARP1
SCHEMBL28988341 0.77 PARP1 (0.48) TLR8PARP1
SCHEMBL15553342 0.77 TLR8 (0.49) TLR8
SCHEMBL29037270 0.77 TLR8 (0.45) TLR8
SCHEMBL28298728 0.77 PARP1 (0.48) TLR8PARP1
SCHEMBL28200574 0.77 TLR8 (0.42) TLR8PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102569210-A Semiconductor device packaging method and semiconductor device package NXP BV 2012-07-11 CN disclosed
EP-2453474-A1 Semiconductor device packaging method and semiconductor device package NXP B.V. (NL) 2012-05-16 EP disclosed
US-20120112351-A1 SEMICONDUCTOR DEVICE PACKAGING METHOD AND SEMICONDUCTOR DEVICE PACKAGE NXP B.V. (NL) 2012-05-10 US disclosed
EP-2421032-A1 Semiconductor Device Packaging Method and Semiconductor Device Package NXP B.V. (NL) 2012-02-22 EP disclosed