Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15553342 | 0.95 | TLR8 (0.49) | TLR8 | |
| SCHEMBL27681188 | 0.94 | TLR8 (0.50) | TLR8ALDH1A1 | |
| SCHEMBL14365376 | 0.83 | MEN1 (0.44) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL629042 | 0.81 | TLR8 (0.41) | TLR8PARP1 | |
| SCHEMBL27995176 | 0.79 | TLR8 (0.38) | TLR8MASP2MEN1ALDH1A1NUDT1 | |
| SCHEMBL6694499 | 0.78 | MASP2 (0.46) | TLR8MASP2MEN1ALDH1A1NUDT1 | |
| SCHEMBL3857633 | 0.78 | PARP1 (0.49) | TLR8PARP1 | |
| SCHEMBL28988341 | 0.77 | PARP1 (0.48) | TLR8PARP1 | |
| SCHEMBL29037270 | 0.77 | TLR8 (0.45) | TLR8 | |
| SCHEMBL16097303 | 0.77 | PARP1 (0.48) | TLR8PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989096-B | Thioazole compound and preparation method and application thereof | 赣南师范大学 | 2023-10-24 | — | — | CN | disclosed |