Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 4/20 | 0.78 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291659 | 1.00 | ATP6V1B1 (0.78) | ATP6V1B1ATP6AP1L3MBTL1DRD2DRD4 | |
| SCHEMBL6291661 | 1.00 | ATP6V1B1 (0.78) | ATP6V1B1ATP6AP1L3MBTL1DRD2DRD4 | |
| SCHEMBL6292751 | 0.94 | ATP6V1B1 (0.76) | ATP6V1B1ATP6AP1DRD2DRD4HTR2A | |
| SCHEMBL6292750 | 0.94 | ATP6V1B1 (0.76) | ATP6V1B1ATP6AP1DRD2DRD4HTR2A | |
| SCHEMBL6363567 | 0.94 | ATP6V1B1 (0.80) | ATP6V1B1ATP6AP1L3MBTL1DRD2DRD4 | |
| SCHEMBL6363568 | 0.94 | ATP6V1B1 (0.80) | ATP6V1B1ATP6AP1L3MBTL1DRD2DRD4 | |
| SCHEMBL6291563 | 0.92 | ATP6V1B1 (0.78) | ATP6V1B1ATP6AP1DRD2DRD4SLC6A4 | |
| SCHEMBL6291565 | 0.92 | ATP6V1B1 (0.78) | ATP6V1B1ATP6AP1DRD2DRD4SLC6A4 | |
| SCHEMBL6291562 | 0.92 | ATP6V1B1 (0.78) | ATP6V1B1ATP6AP1DRD2DRD4SLC6A4 | |
| SCHEMBL6292790 | 0.89 | ATP6V1B1 (0.75) | ATP6V1B1ATP6AP1DRD2DRD4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903117-B2 | Indole derivatives for the treatment of osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2005-06-07 | — | — | US | disclosed |