ATP6V1B1

V-type proton ATPase subunit B, kidney isoform · P15313 · ATP6V1B1 on Sugi Atlas →

578 patent compounds predicted against ATP6V1B1, 469 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL6295582 SCHEMBL6295582 1.00 5/20
SCHEMBL6295583 SCHEMBL6295583 1.00 5/20
SCHEMBL6292583 SCHEMBL6292583 0.93 5/20
SCHEMBL6292833 SCHEMBL6292833 0.88 5/20
SCHEMBL6292835 SCHEMBL6292835 0.88 5/20
SCHEMBL6292838 SCHEMBL6292838 0.88 5/20
SCHEMBL6295623 SCHEMBL6295623 0.82 5/20
SCHEMBL6291696 SCHEMBL6291696 0.81 5/20
SCHEMBL6291700 SCHEMBL6291700 0.81 5/20
SCHEMBL6291701 SCHEMBL6291701 0.81 5/20
SCHEMBL6363567 SCHEMBL6363567 0.80 5/20
SCHEMBL6363568 SCHEMBL6363568 0.80 5/20
SCHEMBL1229725 SCHEMBL1229725 0.80 5/20
SCHEMBL1229727 SCHEMBL1229727 0.80 5/20
SCHEMBL1229728 SCHEMBL1229728 0.80 5/20
SCHEMBL6296361 SCHEMBL6296361 0.80 5/20
SCHEMBL6296395 SCHEMBL6296395 0.80 5/20
SCHEMBL8343521 SCHEMBL8343521 0.80 5/20
SCHEMBL29546820 SCHEMBL29546820 0.80 5/20
SCHEMBL6291898 SCHEMBL6291898 0.78 5/20

Clinical trials — most relevant to ATP6V1B1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN) PHASE3COMPLETED
Preventing Acute Kidney Injury (AKI) in Pediatric Patients PHASE3UNKNOWN
The Possible Efficacy and Safety of Lansoprazole Co-administration With Neoadjuvant Chemotherapy in Women With Breast Cancer PHASE3COMPLETED
Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression PHASE2/PHASE3NOT_YET_RECRUITING
Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial) PHASE2RECRUITING
Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor PHASE2COMPLETED
The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Disease. PHASE2RECRUITING
Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis nanCOMPLETED
Sodium Accumulation Study in Haemodialysis: Brain Study nanRECRUITING
Genetic Variations That Increase the Risk for Calcium Kidney Stones: a Family-based Study nanCOMPLETED
Gene Modifiers of Cystic Fibrosis Lung Disease nanACTIVE_NOT_RECRUITING
Biological Collection of Kidney Cells nanUNKNOWN
Oxalate and Citrate in Humans - Response to Citrate nanRECRUITING
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital nanUNKNOWN
Sodium Transport: Genetics and Hypertension nanCOMPLETED
Double Blind Crossover Comparison of Diuretics in the Young nanUNKNOWN
Autoantibodies and Direct-acting Antivirals nanCOMPLETED
When the Kidney Reacts to Nutritional Changes nanCOMPLETED
Natural History Study of ATP1A3-related Disease nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Perfusion - Pressure - Creatinine Trial nanCOMPLETED
Genetic Testing and Counseling to Reduce Diabetic Complications nanCOMPLETED
Western Sydney Kidney Injury Biopsy Study nanNOT_YET_RECRUITING
Study of Heat Shock Proteins as Prognostic Factor of Acute Renal Failure in Children (HSP-Study) nanUNKNOWN
Proteomics of Primary Hyperoxaluria Type 1 nanCOMPLETED
Genomic First Testing in Chronic Kidney Disease nanNOT_YET_RECRUITING
Vitamin D and the Free Hormone Hypothesis nanCOMPLETED
Hereditary Tubulointerstitial Nephritis nanCOMPLETED
Ventricular Arrhythmias in Uremic Cardiomyopathy nanCOMPLETED
Pilot Study to Evaluate the Contribution of Gene Variants to Idiopathic Urolithiasis nanENROLLING_BY_INVITATION

Related proteins — ESM-2 sequence neighbours (a ATP6V1B1 binder may also engage these)

ProteinNameSimilarity
P31407 1.000 P31407 →
Q91YH6 1.000 Q91YH6 →
P16140 1.000 P16140 →
P31410 1.000 P31410 →
Q9N5A0 1.000 Q9N5A0 →
Q19626 1.000 Q19626 →
Q43433 1.000 Q43433 →
Q48VL2 1.000 Q48VL2 →
ATP6V1B2 V-type proton ATPase subunit B, brain isoform 1.000 landscape →
P62814 1.000 P62814 →
P0DA07 1.000 P0DA07 →
Q5XE49 1.000 Q5XE49 →
A2RC98 1.000 A2RC98 →
Q26976 1.000 Q26976 →
P31409 1.000 P31409 →
Q5R5V5 1.000 Q5R5V5 →
Q1JNS7 1.000 Q1JNS7 →
P31408 1.000 P31408 →
Q43432 1.000 Q43432 →
P48413 1.000 P48413 →
P22550 1.000 P22550 →
Q60187 1.000 Q60187 →
B5XJH4 1.000 B5XJH4 →
Q1JDX0 1.000 Q1JDX0 →
P13548 1.000 P13548 →
Q9SM09 1.000 Q9SM09 →
P31411 1.000 P31411 →
Q1JIX4 1.000 Q1JIX4 →
Q8P2U6 1.000 Q8P2U6 →
P11574 1.000 P11574 →