SCHEMBL6291671

SCHEMBL6291671

CCCCCCCCCCCCCCP(CCCCCCCCCCCCCC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
EPHX2 P34913 1/20 0.39
PKM P14618 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CETP P11597 3/20 0.39
HTT P42858 2/20 0.38
KCNH2 Q12809 1/20 0.38
NAAA Q02083 1/20 0.38
LIPG Q9Y5X9 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
LTA4H P09960 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6288234 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL2922719 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL27765995 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL15659895 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL49664 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6288242 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6288219 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL3813028 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6288656 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6791527 0.98 DNM1 (0.39) DNM1MEN1KMT2ATP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020137820-A1 Phosphorus compounds SANDOZ LTD. (CH) 2002-09-26 US claimed
US-6864304-B2 Phosphorus compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2005-03-08 US disclosed
US-20020137820-A1 Phosphorus compounds SANDOZ LTD. (CH) 2002-09-26 US disclosed
US-6369140-B1 POLYOLEFIN AND PHOSPHINE OR PHOSPHORANE COMPOUNDS STABILIZERS; OXIDATION, HEAT, STRESS, AND ULTRAVIOLET RADIATION RESISTANCE CLARIANT FINANCE (BVI) LIMITED (BV) 2002-04-09 US disclosed
US-5488079-A HEAT AND LIGHT STABILIZERS FOR OLEFINS USING PHOSPHINES SANDOZ LTD. (CH) 1996-01-30 US disclosed