Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TFEB | P19484 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382365 | 1.00 | TDP1 (0.65) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19244254 | 0.91 | TDP1 (0.61) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19244199 | 0.90 | TDP1 (0.57) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19244481 | 0.90 | TDP1 (0.57) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19244200 | 0.90 | TDP1 (0.57) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19244380 | 0.89 | TDP1 (0.56) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19244381 | 0.89 | TDP1 (0.56) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Octinoxate SCHEMBL19717857 | 0.88 | TDP1 (0.74) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19244289 | 0.88 | TDP1 (0.55) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19244402 | 0.88 | TDP1 (0.55) | TDP1ALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112352010-B | Crosslinked silicone resin, method for producing same, and cosmetic | 信越化学工业株式会社 | 2023-07-14 | — | — | CN | disclosed |
| EP-3208301-B1 | RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME | TOSOH CORP (JP) | 2019-04-03 | — | — | EP | disclosed |
| US-10126478-B2 | Resin composition and optical compensation film using same | TOSOH CORPORATION (JP) | 2018-11-13 | — | — | US | disclosed |
| US-20170242174-A1 | RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME | TOSOH CORPORATION (JP) | 2017-08-24 | — | — | US | disclosed |
| EP-3208301-A1 | RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME | Tosoh Corporation (JP) | 2017-08-23 | — | — | EP | disclosed |
| US-6964954-B2 | Use of DHEA derivatives on keratinous substances | L'OREAL (FR) | 2005-11-15 | — | — | US | disclosed |
| US-20030113284-A1 | Use of DHEA derivatives on keratinous substances | L'OREAL (FR) | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030113284-A1 | Use of DHEA derivatives on keratinous substances | SHBG, CYP21A2, NR5A1 | TDP1 2167/4885ALDH1A1 703/4885KDM4E 2328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.