Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | CCR1 | P32246 | 4/20 | 0.44 |
| ▸ | CCR8 | P51685 | 4/20 | 0.44 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194064 | 0.80 | MAPT (0.44) | MAPTKDM4ECCR1CCR8CCR5 | |
| Hydrochloric Acid SCHEMBL1072937 | 0.80 | MAPT (0.44) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL6055552 | 0.76 | MAPT (0.40) | MAPTKDM4ECCR1CCR8CCR5 | |
| Hydrochloric Acid SCHEMBL3081474 | 0.73 | CCR1 (0.38) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL5270898 | 0.73 | CCR1 (0.38) | MAPTKDM4ECCR1CCR8CCR5 | |
| Hydrochloric Acid SCHEMBL29754024 | 0.73 | CCR1 (0.38) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL6292389 | 0.72 | CCR1 (0.43) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL256942 | 0.68 | CCR1 (0.61) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL29664407 | 0.68 | CCR1 (0.61) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL25155480 | 0.67 | KDM4E (0.48) | MAPTKDM4ECCR1CCR8CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838563-B2 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | BASELL POLYOLEFINS (DE) | 2005-01-04 | — | — | US | disclosed |
| US-6787498-B2 | AS CATALYSTS FOR POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| US-6699948-B2 | AS CATALYSTS FOR POLYMERIZATION OF OLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030055267-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-03-20 | — | — | US | disclosed |
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-02-20 | — | — | US | disclosed |
| US-20030036662-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-02-20 | — | — | US | disclosed |
| US-6437161-B1 | OLEFIN POLYMERIZATION CATALYSTS; SUBSTITUENT ON THE CYCLOPENTADIENYL RING CARRIES A DONOR FUNCTION WHICH IS BONDED RIGIDLY, NOT EXCLUSIVELY VIA SP3-HYBRIDIZED CARBON OR SILICON ATOMS, | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055267-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | MAPT 3160/4885KDM4E 3587/4885CCR1 180/4885 |
| US-20030036662-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | MAPT 3160/4885KDM4E 3587/4885CCR1 180/4885 |
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | MAPT 3160/4885KDM4E 3587/4885CCR1 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.