Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | CCR1 | P32246 | 4/20 | 0.40 |
| ▸ | CCR8 | P51685 | 4/20 | 0.40 |
| ▸ | CCR5 | P51681 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26134606 | 0.89 | CCR1 (0.35) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL6131343 | 0.79 | MAPT (0.36) | MAPTKDM4ECCR1CCR8CCR5 | |
| Hydrochloric Acid SCHEMBL1072937 | 0.76 | MAPT (0.44) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL7194064 | 0.76 | MAPT (0.44) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL6292387 | 0.76 | MAPT (0.44) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL6055554 | 0.71 | CCR1 (0.40) | MAPTKDM4ECCR1CCR8CCR5 | |
| Hydrochloric Acid SCHEMBL29754024 | 0.70 | CCR1 (0.38) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL5270898 | 0.70 | CCR1 (0.38) | MAPTKDM4ECCR1CCR8CCR5 | |
| Hydrochloric Acid SCHEMBL3081474 | 0.70 | CCR1 (0.38) | MAPTKDM4ECCR1CCR8CCR5 | |
| SCHEMBL6131341 | 0.68 | KDM4E (0.38) | MAPTKDM4ECCR1CCR8CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094724-B2 | Catalytic solid supported on calcined hydrotalcite for olefinic polymerisation | BASSELL POLYELEFINE GMBH (DE) | 2006-08-22 | — | — | US | disclosed |
| US-6924248-B2 | Catalyst system for carrying out olefin polymerization comprising a calcined hydro-talcite serving as a supporting material | BASELL POLYOLEFINE GMBH (DE) | 2005-08-02 | — | — | US | disclosed |
| US-6919412-B1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with a donor bridge | BASELL POLYOLEFINE GMBH (DE) | 2005-07-19 | — | — | US | disclosed |
| US-20040033890-A1 | Catalyst system for carrying out olefin polymerization comprising a calcined hydro-talcite serving as a supporting material | LYONDELL CHEMICAL TECHNOLOGY, L.P. | 2004-02-19 | — | — | US | disclosed |
| US-20030176275-A1 | Catalytic solid supported on calcined hydrotalcite for olefinic polymerisation | BASELL POLYOLEFINE GMBH (DE) | 2003-09-18 | — | — | US | disclosed |