Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692269 | 0.87 | KMT2A (0.54) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL3001518 | 0.84 | GSK3B (0.52) | TSHRALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL10768688 | 0.84 | TSHR (0.51) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL182493 | 0.82 | MAPT (0.62) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL12502625 | 0.79 | TSHR (0.54) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL23174424 | 0.77 | TSHR (0.62) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8940579 | 0.77 | TSHR (0.80) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL29123133 | 0.77 | TSHR (0.71) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL7878712 | 0.76 | TSHR (0.58) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL12502788 | 0.76 | TSHR (0.51) | TSHRALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884893-B1 | Method for selectively dissociating cyclic carboxylic acid anhydrides | MERCK PATENT GMBH (DE) | 2005-04-26 | — | — | US | disclosed |
| US-4739071-A | Process for the preparation of enantiomers | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-04-19 | — | — | US | disclosed |