Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486249 | 0.83 | ALDH1A1 (0.60) | ATMPOLBCA2SMN1; SMN2CA1 | |
| SCHEMBL8518764 | 0.82 | POLB (0.63) | ATMPOLBCA2SMN1; SMN2CA12 | |
| SCHEMBL10501189 | 0.81 | CA12 (0.58) | CA2CA12CA1CA9CA14 | |
| SCHEMBL7435099 | 0.80 | ATM (0.76) | ATMPOLBCA2SMN1; SMN2CA12 | |
| Hydrochloric Acid SCHEMBL11808765 | 0.79 | ATM (0.73) | ATMPOLBCA2SMN1; SMN2CA12 | |
| SCHEMBL8635081 | 0.79 | ATM (1.00) | ATMPOLBCA2SMN1; SMN2CA12 | |
| SCHEMBL30230461 | 0.79 | ATM (1.00) | ATMPOLBCA2SMN1; SMN2CA12 | |
| SCHEMBL557799 | 0.79 | ATM (1.00) | ATMPOLBCA2SMN1; SMN2CA12 | |
| SCHEMBL7265002 | 0.79 | CA12 (0.73) | ATMPOLBCA2SMN1; SMN2CA12 | |
| SCHEMBL31157848 | 0.78 | CYP19A1 (0.77) | ATMPOLBCA2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716162-A | BRAIN FUNCTION | SANKYO COMPANY, LIMITED (JP) | 1987-12-29 | — | — | US | claimed |
| US-6867200-B1 | (Hetero)aryl-bicyclic heteroaryl derivatives, their preparation and their use as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-15 | — | — | US | disclosed |
| EP-0171217-B1 | FUSED-RING HETEROCYCLIC COMPOUNDS A PROCESS FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE | SANKYO COMPANY LIMITED (JP) | 1989-05-03 | — | — | EP | disclosed |
| US-4716162-A | BRAIN FUNCTION | SANKYO COMPANY, LIMITED (JP) | 1987-12-29 | — | — | US | disclosed |
| EP-0171217-A2 | Fused-ring heterocyclic compounds a process for their production and their pharmaceutical use | SANKYO COMPANY LIMITED (JP) | 1986-02-12 | — | — | EP | disclosed |
| US-4209622-A | 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine | Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. (HU) | 1980-06-24 | — | — | US | disclosed |