⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701429 | 0.72 | — | — | |
| SCHEMBL44376 | 0.67 | — | — | |
| SCHEMBL9425908 | 0.67 | — | — | |
| SCHEMBL28235479 | 0.67 | — | — | |
| SCHEMBL25404780 | 0.65 | — | — | |
| SCHEMBL19601497 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL5694135 | 0.65 | ALDH1A1 (0.31) | — | |
| Alcohol SCHEMBL4884045 | 0.65 | ALDH1A1 (0.40) | — | |
| SCHEMBL991741 | 0.65 | — | — | |
| SCHEMBL412520 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170007557-A1 | PHARMACEUTICAL COMPOSITIONS FOR COMBINATION THERAPY | SANIONA AS (DK) | 2017-01-12 | — | — | US | disclosed |
| WO-2016127075-A2 | TRANSGENIC PLANTS AND A TRANSIENT TRANSFORMATION SYSTEM FOR GENOME-WIDE TRANSCRIPTION FACTOR TARGET DISCOVERY | NEW YORK UNIVERSITY (US) | 2016-08-11 | — | — | WO | disclosed |
| US-9387184-B2 | Pharmaceutical compositions for combination therapy | SANIONA A/S (DK) | 2016-07-12 | — | — | US | disclosed |
| CN-1269853-C | Catalyst for producing alpha-olefin and method for producing alpha-olefin | IDEMITSU PETROCHEMICAL CO (JP) | 2006-08-16 | — | — | CN | disclosed |
| US-6861537-B2 | Tricyclic and tetracyclic taxane intermediates | FLORIDA STATE UNIVERSITY (US) | 2005-03-01 | — | — | US | disclosed |
| CN-1174805-C | Catalyst for producing alpha-olefin and method for producing alpha-olefin | 出光石油化学株式会社 | 2004-11-10 | — | — | CN | disclosed |
| EP-0960881-B1 | Synthesis of taxol and its derivatives | UNIV FLORIDA STATE (US) | 2003-04-23 | — | — | EP | disclosed |
| US-20030050485-A1 | For the preparation of taxol and other tricyclic and tetracyclic taxanes | FLORIDA STATE UNIVERSITY | 2003-03-13 | — | — | US | disclosed |
| US-6433189-B2 | Tricyclic and tetracyclic taxane intermediates | FLORIDA STATE UNIVERSITY | 2002-08-13 | — | — | US | disclosed |
| US-20010053857-A1 | Tricyclic and tetracyclic taxane intermediates | HOLTON ROBERT A (US) | 2001-12-20 | — | — | US | disclosed |
| CN-1239482-A | Catalysts for polymerization of olefins, process for prodn. of olefin polymers, and processes for prodn. of styrene polymers | IDEMITSU PETROCHEMICAL CO (JP) | 1999-12-22 | — | — | CN | disclosed |
| US-6005120-A | INTERMEDIATE FOR USE IN THE PREPARATION OF TAXOL OR OTHER TRICYCLIC OR TETRACYCLIC TAXANES | FLORIDA STATE UNIVERSITY (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0960881-A1 | Synthesis of taxol and its derivatives | FLORIDA STATE UNIVERSITY (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5760252-A | Synthetic process for the preparation of tricyclic and tetracyclic taxanes | FLORIDA STATE UNIVERSITY (US) | 1998-06-02 | — | — | US | disclosed |
| US-5637732-A | Tricyclic and tetracyclic taxanes | FLORIDA STATE UNIVERSITY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5618952-A | Synthetic process for the preparation of tricyclic and tetracyclic taxanes | FLORIDA STATE UNIVERSITY (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0710223-A4 | SYNTHESIS OF TAXOL AND ITS DERIVATIVES | UNIV FLORIDA STATE (US) | 1996-08-21 | — | — | EP | disclosed |
| EP-0710223-A1 | SYNTHESIS OF TAXOL AND ITS DERIVATIVES | FLORIDA STATE UNIVERSITY (US) | 1996-05-08 | — | — | EP | disclosed |
| US-5405972-A | Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes | FLORIDA STATE UNIVERSITY (US) | 1995-04-11 | — | — | US | disclosed |
| WO-1995003265-A1 | SYNTHESIS OF TAXOL AND ITS DERIVATIVES | FLORIDA STATE UNIVERSITY (US) | 1995-02-02 | — | — | WO | disclosed |