SCHEMBL6294258

SCHEMBL6294258

CCCCc1ccccc1Cn1cc(-c2cn([C@H]3C[C@H](O)[C@@H](CO)O3)c(=O)[nH]c2=O)nn1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TK1 P04183 2/20 0.55
TK2 O00142 2/20 0.55
TYMS P04818 1/20 0.48
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6295677 0.98 TK1 (0.54) TK1TK2TYMSLMNASMN1; SMN2
SCHEMBL6295467 0.97 TK1 (0.54) TK1TK2TYMSLMNASMN1; SMN2
SCHEMBL6300116 0.95 TK1 (0.61) TK1TK2TYMSLMNASMN1; SMN2
SCHEMBL6294780 0.93 TK1 (0.55) TK1TK2TYMSLMNASMN1; SMN2
SCHEMBL6294252 0.93 TK1 (0.55) TK1TK2TYMSLMNASMN1; SMN2
SCHEMBL6295474 0.89 TK1 (0.54) TK1TK2LMNASMN1; SMN2
SCHEMBL6295475 0.89 TK1 (0.54) TK1TK2LMNASMN1; SMN2
SCHEMBL6294750 0.89 TK2 (0.52) TK1TK2TYMS
SCHEMBL6294746 0.89 TK2 (0.52) TK1TK2TYMS
SCHEMBL6295678 0.87 TK1 (0.54) TK1TK2LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6884882-B1 2′-deoxyuridine derivatives and hydrogels formed therewith POSTECH FOUNDATION (KR) 2005-04-26 US disclosed