SCHEMBL6294288

SCHEMBL6294288

COc1cccc2c1C=C(C)C2[Zr](Cl)(Cl)(C1C(C)=Cc2c(OC)cccc21)=[Si](C)C

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTR2A P28223 3/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6295488 0.84 SLC6A2 (0.33) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL3377811 0.81
SCHEMBL6294210 0.80 KDM4E (0.32) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL16393480 0.78 HTR2C (0.30) HTR2C
SCHEMBL6234373 0.77 GABRA1 (0.30)
SCHEMBL8597213 0.77 GABRA1 (0.30)
SCHEMBL338922 0.76 PDCD1 (0.30)
SCHEMBL4658167 0.76 HTR2A (0.30) HTR2AHTR2CHTR2B
SCHEMBL1241277 0.76 HTR2C (0.34) HTR2C
SCHEMBL1239993 0.75 POLB (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6930152-B2 Propylene polymer compositions MITSUI CHEMICALS, INC. (JP) 2005-08-16 US disclosed
US-6838522-B2 Propylene polymer compositions MITSUI CHEMICALS, INC. (JP) 2005-01-04 US disclosed
US-20040230004-A1 Propylene polymer compositions MITSUI CHEMICALS, INC. 2004-11-18 US disclosed
US-20030130428-A1 Propylene polymer compositions HASHIMOTO MIKIO (JP) 2003-07-10 US disclosed
EP-1314756-A1 Propylene polymer compositions Mitsui Chemicals, Inc. (JP) 2003-05-28 EP disclosed
EP-0841371-B1 Propylene polymer compositions MITSUI CHEMICALS INC (JP) 2002-11-20 EP disclosed
EP-0841373-B1 Propylene polymer compositions MITSUI CHEMICALS INC (JP) 2002-07-24 EP disclosed
US-20020045712-A1 Propylene polymer compositions HASHIMOTO MIKIO (JP) 2002-04-18 US disclosed
US-6156844-A Propylene polymer compositions containing a propylene homo- or co-polymer obtained using a bridged metallocene catalyst and another propylene homo- or co-polymer MITSUI CHEMICALS INC (JP) 2000-12-05 US disclosed
EP-0646624-B1 PROPYLENE POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 1998-09-02 EP disclosed
EP-0841373-A2 Propylene polymer compositions Mitsui Chemicals, Inc. (JP) 1998-05-13 EP disclosed
EP-0841372-A2 Propylene polymer compositions Mitsui Chemicals, Inc. (JP) 1998-05-13 EP disclosed
EP-0841371-A2 Propylene polymer compositions Mitsui Chemicals, Inc. (JP) 1998-05-13 EP disclosed
EP-0841370-A2 Propylene polymer compositions Mitsui Chemicals, Inc. (JP) 1998-05-13 EP disclosed
EP-0646624-A1 PROPYLENE POLYMER COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-04-05 EP disclosed