Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.64 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 6/20 | 0.59 |
| ▸ | DRD3 | P35462 | 6/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629921 | 1.00 | CYP19A1 (0.64) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 | |
| SCHEMBL6790577 | 0.94 | CYP19A1 (0.64) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 | |
| SCHEMBL11139292 | 0.88 | CYP19A1 (0.52) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 | |
| SCHEMBL8688900 | 0.86 | CYP19A1 (0.60) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 | |
| SCHEMBL4623036 | 0.86 | CYP26A1 (0.67) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 | |
| SCHEMBL4622442 | 0.86 | CYP19A1 (0.63) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 | |
| SCHEMBL3149465 | 0.86 | CYP19A1 (0.63) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 | |
| SCHEMBL3157913 | 0.86 | CYP19A1 (0.63) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 | |
| SCHEMBL7288575 | 0.86 | CYP26A1 (0.67) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 | |
| SCHEMBL9361493 | 0.86 | CYP19A1 (0.63) | CYP19A1CYP26A1DRD2DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190717-A1 | P38 GAMMA INHIBITORS AND METHOD OF USE THEREOF | CITY OF HOPE | 2023-06-22 | — | — | US | disclosed |
| EP-1963292-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-02-22 | — | — | EP | disclosed |
| US-7700633-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-04-20 | — | — | US | disclosed |
| US-20080262050-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-10-23 | — | — | US | disclosed |
| EP-1963292-A2 | ORGANIC COMPOUNDS | Novartis Pharma AG (CH) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067615-A2 | THIADIAZOLE DERIVATIVES AS ANTIDIABETIC AGENTS | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262050-A1 | Organic Compounds | PTPRS, PTPRO, PTPRC | CYP19A1 1316/4885CYP26A1 2790/4885DRD2 4698/4885 |
| US-20230190717-A1 | P38 GAMMA INHIBITORS AND METHOD OF USE THEREOF | CDC42BPG, MAPK1, MAPK7 | CYP19A1 3269/4885CYP26A1 2325/4885DRD2 4764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.